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科研机构
上海药物研究所 [8]
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期刊论文 [8]
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2021 [1]
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Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents from white ginseng and red ginseng
期刊论文
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 6, 页码: 597-609
作者:
Zuo, Tiantian
;
Zhang, Chunxia
;
Li, Weiwei
;
Wang, Hongda
;
Hu, Ying
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Dimension-enhanced strategy
Multicomponent characterization
Ginsenoside
Offline two-dimensional liquid chromatography
Ion mobility-quadrupole time-of-flight mass spectrometry
In-house database
A novel short-term high-lactose culture approach combined with a matrix-assisted laser desorption ionization-time of flight mass spectrometry assay for differentiating Escherichia coli and Shigella species using artificial neural networks
期刊论文
PLOS ONE, 2019, 卷号: 14, 期号: 10, 页码: 10
作者:
Ling, Jin
;
Wang, Hong
;
Li, Gaomin
;
Feng, Zhen
;
Song, Yufei
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea: A novel cyclophilin A allosteric activator
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 卷号: 425, 期号: 4, 页码: 938-943
作者:
Lv, Maosheng
;
Shi, Ting
;
Mao, Xiaona
;
Li, Xi
;
Chen, Yingyi
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
CypA
PPIase activity
Allosteric activator
Chemical tool
Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 52, 页码: 33-43
作者:
Liu, Ming-Ming
;
Zhou, Lu
;
He, Pei-Lan
;
Zhang, Yi-Nan
;
Zhou, Jia-Yi
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Anti-HCV agents
NS5B polymerase
Flavonoids
Ligand-based pharmacophore
Virtual screening
Pharmacophore-based discovery of FXR-agonists. Part II: Identification of bioactive triterpenes from Ganoderma lucidum
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 卷号: 19, 期号: 22, 页码: 6779-6791
作者:
Grienke, Ulrike
;
Mihaly-Bison, Judit
;
Schuster, Daniela
;
Afonyushkin, Taras
;
Binder, Markus
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Farnesoid X receptor
Ganoderma lucidum
Lanostane triterpenes
Ganoderic acids
Molecular modeling
Virtual screening
Natural products
PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach
期刊论文
NUCLEIC ACIDS RESEARCH, 2010, 卷号: 38, 页码: W609-W614
作者:
Liu, Xiaofeng
;
Ouyang, Sisheng
;
Yu, Biao
;
Liu, Yabo
;
Huang, Kai
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Peptide deformylase is a potential target for anti-Helicobacter pylori drugs: Reverse docking, enzymatic assay, and X-ray crystallography validation
期刊论文
PROTEIN SCIENCE, 2006, 卷号: 15, 期号: 9, 页码: 2071-2081
作者:
Cai, Jianhua
;
Han, Cong
;
Hu, Tiancen
;
Zhang, Jian
;
Wu, Dalei
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
peptide deformylase
protein crystallization
reverse docking
enzyme inhibitor
Helicobacter pylori
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