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CORC

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Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：40/0  |  提交时间：2022/01/04
Discovery of High-Affinity Inhibitors of the BPTF Bromodomain 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12075-12088
作者:  Lu, Tian;  Lu, Haibo;  Duan, Zhe;  Wang, Jun;  Han, Jie
收藏  |  浏览/下载：38/0  |  提交时间：2021/11/04
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Zhang, Wan-ting;  Liu, Ting-ting;  Wu, Man;  Chen, Xiao-chen;  Han, Li
收藏  |  浏览/下载：53/0  |  提交时间：2021/05/24
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:  Zhou, Yu;  Li, Xiaoguang;  Chen, Kerong;  Ba, Qian;  Zhang, Xu
收藏  |  浏览/下载：39/0  |  提交时间：2021/06/11
Structural optimization and biological evaluation for novel artemisinin derivatives against liver and ovarian cancers 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 13
作者:  Zhou, Yu;  Li, Xiaoguang;  Chen, Kerong;  Ba, Qian;  Zhang, Xu
收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载：34/0  |  提交时间：2021/05/24
Allosteric Inhibitors of SHP2: An Updated Patent Review (2015-2020) 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2021, 卷号: 28, 期号: 19, 页码: 3825-3842
作者:  Wu, Jingwei;  Zhang, Huan;  Zhao, Guilong;  Wang, Runling
收藏  |  浏览/下载：65/0  |  提交时间：2021/08/17
An antibody-drug conjugate targeting a GSTA glycosite-signature epitope of MUC1 expressed by non-small cell lung cancer 期刊论文
CANCER MEDICINE, 2020, 页码: 12
作者:  Pan, Deng;  Tang, Yubo;  Tong, Jiao;  Xie, Chengmei;  Chen, Jiaxi
收藏  |  浏览/下载：19/0  |  提交时间：2020/12/24
Structural basis for activation of the growth hormone-releasing hormone receptor 期刊论文
NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10
作者:  Zhou, Fulai;  Zhang, Huibing;  Cong, Zhaotong;  Zhao, Li-Hua;  Zhou, Qingtong
收藏  |  浏览/下载：24/0  |  提交时间：2020/12/21
MiR-629-5p promotes the invasion of lung adenocarcinoma via increasing both tumor cell invasion and endothelial cell permeability 期刊论文
ONCOGENE, 2020, 页码: 16
作者:  Li, Yu;  Zhang, Huibiao;  Fan, Lei;  Mou, Jiahui;  Yin, Yue
收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01

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