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科研机构
上海药物研究所 [18]
内容类型
期刊论文 [18]
发表日期
2021 [1]
2020 [1]
2015 [4]
2014 [1]
2013 [2]
2012 [1]
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Biochemist... [1]
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专题:上海药物研究所
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The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression
期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17
作者:
Li, Xinzhi
;
Yuan, Bingchuan
;
Lu, Min
;
Wang, Yuqin
;
Ding, Na
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/18
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters
期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:
Wang, Ying
;
Zhu, Yao
;
Niu, Junxing
;
Deng, Qiangqiang
;
Guo, Shimeng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/12/21
Bile acid analog
NASH
TGR5
Cd36
AMPK alpha
HC toxin (a HDAC inhibitor) enhances IRS1-Akt signalling and metabolism in mouse myotubes
期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2015, 卷号: 55, 期号: 3, 页码: 197-207
作者:
Tan, Hayden Weng Siong
;
Sim, Arthur Yi Loong
;
Huang, Su Ling
;
Leng, Ying
;
Long, Yun Chau
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
histone deacetylase (HDAC)
Akt
insulin receptor substrate 1 (IRS1)
metabolism
exercise
myotubes
Design and Synthesis of Novel Arctigenin Analogues for the Amelioration of Metabolic Disorders
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 6, 期号: 4, 页码: 386-391
作者:
Duan, Shudong
;
Huang, Suling
;
Gong, Jian
;
Shen, Yu
;
Zeng, Limin
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Natural product
arctigenin analogues
2-deoxyglucose uptake in L6 myotubes
amelioration of metabolic disorders
Yhhu981, a novel compound, stimulates fatty acid oxidation via the activation of AMPK and ameliorates lipid metabolism disorder in ob/ob mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 3, 页码: 343-352
作者:
Zeng, Hong-liang
;
Huang, Su-ling
;
Xie, Fu-chun
;
Zeng, Li-min
;
Hu, You-hong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
yhhu981
fatty acid oxidation
fatty acid synthesis
AMPK
compound C
sirtinol
EX527
STO609
AICAR
metformin
metabolism disorder
C2C12 myotubes
HepG2 cells
ob/ob mice
yhhu981anovelcompoundstimulatesfattyacidoxidationviatheactivationofampkandameliorateslipidmetabolismdisorderinobobmice
期刊论文
actapharmacologicasinica, 2015, 卷号: 36, 期号: 3, 页码: 343
作者:
Zeng Hongliang
;
Huang Suling
;
Xie Fuchun
;
Zeng Limin
;
Hu Youhong
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
PROTEIN-KINASE ACTIVATION
RAT SOLEUS MUSCLE
SKELETAL-MUSCLE
INSULIN SENSITIVITY
MALONYL-COA
MITOCHONDRIAL BIOGENESIS
MYOBLAST DIFFERENTIATION
ENERGY-EXPENDITURE
DEFICIENT MICE
GLUCOSE-UPTAKE
yhhu981
fatty acid oxidation
fatty acid synthesis
AMPK
compound C
sirtinol
EX527
STO609
AICAR
metformin
metabolism disorder
C2C12 myotubes
HepG2 cells
ob/ob mice
Azoxystrobin, a mitochondrial complex III Q(o) site inhibitor, exerts beneficial metabolic effects in vivo and in vitro
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2014, 卷号: 1840, 期号: 7, 页码: 2212-2221
作者:
Gao, An-Hui
;
Fu, Yan-Yun
;
Zhang, Kun-Zhi
;
Zhang, Mei
;
Jiang, Hao-Wen
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Azoxystrobin
Mitochondria complex III
Metabolic diseases
AMP-activated protein kinase
Novel Small-Molecule AMP-Activated Protein Kinase Allosteric Activator with Beneficial Effects in db/db Mice
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8
作者:
Zhang, Li-Na
;
Xu, Lei
;
Zhou, Hua-Yong
;
Wu, Ling-Yan
;
Li, Yuan-Yuan
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Novel Small-Molecule PGC-1 alpha Transcriptional Regulator With Beneficial Effects on Diabetic db/db Mice
期刊论文
DIABETES, 2013, 卷号: 62, 期号: 4, 页码: 1297-1307
作者:
Zhang, Li-Na
;
Zhou, Hua-Yong
;
Fu, Yan-Yun
;
Li, Yuan-Yuan
;
Wu, Fang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
BMS309403 Stimulates Glucose Uptake in Myotubes through Activation of AMP-Activated Protein Kinase
期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 8
作者:
Lin, Wanhua
;
Huang, Xiaoli
;
Zhang, Lina
;
Chen, Dongmei
;
Wang, Dongye
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
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