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科研机构
上海药物研究所 [87]
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期刊论文 [86]
会议论文 [1]
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2020 [3]
2019 [4]
2018 [2]
2017 [10]
2016 [5]
2015 [4]
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Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Effects of Shuanghuanglian oral liquids on patients with COVID-19: a randomized, open-label, parallel-controlled, multicenter clinical trial
期刊论文
FRONTIERS OF MEDICINE, 2021, 页码: 14
作者:
Ni, Li
;
Wen, Zheng
;
Hu, Xiaowen
;
Tang, Wei
;
Wang, Haisheng
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2021/08/17
COVID-19
SARS-CoV-2
Shuanghuanglian oral liquid
clinical trial
Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026
作者:
Shi, Yuankai
;
Zhang, Shucai
;
Hu, Xingsheng
;
Feng, Jifeng
;
Ma, Zhiyong
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/12/24
Alflutinib
NSCLC
EGFR T790M mutation
Efficacy
Safety
Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors
期刊论文
CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+
作者:
Li, Huiping
;
Liu, Rongrui
;
Shao, Bin
;
Ran, Ran
;
Song, Guohong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
Phase I
PARP inhibitor (fluzoparib)
solid tumor
pharmacokinetics
safety
antitumor activity
Berberine derivatives with a long alkyl chain branched by hydroxyl group and methoxycarbonyl group at 9-position show improved anti-proliferation activity and membrane permeability in A549 cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Liu, Yi
;
Zhu, Ke-xin
;
Cao, Lei
;
Xie, Zhi-fu
;
Gu, Min
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
berberine
anticancer
membrane permeability
apoptosis
mitochondria
Safety, Efficacy, and Biomarker Analysis of Pyrotinib in Combination with Capecitabine in HER2-Positive Metastatic Breast Cancer Patients: A Phase I Clinical Trial
期刊论文
CLINICAL CANCER RESEARCH, 2019, 卷号: 25, 期号: 17, 页码: 5212-5220
作者:
Li, Qiao
;
Guan, Xiuwen
;
Chen, Shanshan
;
Yi, Zongbi
;
Lan, Bo
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Nanoporous CD-MOF particles with uniform and inhalable size for pulmonary delivery of budesonide
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019, 卷号: 564, 页码: 153-161
作者:
Hu, Xiaoxiao
;
Wang, Caifen
;
Wang, Lebing
;
Liu, Zhaoxin
;
Wua, Li
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
gamma-Cyclodextrin metal-organic framework
Dry powder inhalation
Budesonide
Cholesterol
In vivo fluorescence imaging
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 5, 页码: 2348-2361
作者:
Li, Shiliang
;
Qin, Chun
;
Cui, Shichao
;
Xu, Hongling
;
Wu, Fangshu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia
期刊论文
DRUG DELIVERY, 2019, 卷号: 26, 期号: 1, 页码: 1058-1067
作者:
Fang, Wei
;
Peng, Zhao Liang
;
Dai, Ya Ji
;
Wang, Dian Lei
;
Huang, Peng
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
EGCG-RNPs
preparation
characterization
acute promyelocytic leukemia
uptake
efflux
Jatrophane diterpenoids from Euphorbia helioscopia and their lipid-lowering activities
期刊论文
FITOTERAPIA, 2018, 卷号: 128, 页码: 102-111
作者:
Li, Jun
;
Li, Hui-hui
;
Wang, Wen-qiong
;
Song, Wei-bin
;
Wang, Yi-ping
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Euphorbia helioscopia
Jatrophanes
Hyperlipidemia
Lipid-lowering
LDL receptor
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