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Conformational polymorphs of isotretinoin and their impact on physicochemical and biological properties 期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 610, 页码: 10
作者:  Cheng, Yinxiang;  Rong, Xiaoyi;  Xia, Mengyuan;  Zhang, Zaiyong;  Wang, Jian-Rong
收藏  |  浏览/下载:73/0  |  提交时间:2022/01/04
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Li, Teng-teng;  Peng, Cheng;  Wang, Ji-qiu;  Xu, Zhi-jian;  Su, Ming-bo
收藏  |  浏览/下载:42/0  |  提交时间:2022/01/18
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载:40/0  |  提交时间:2022/01/04
Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文
NATURE, 2021, 页码: 24
作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan
收藏  |  浏览/下载:53/0  |  提交时间:2021/11/04
Exploring the Regulatory Function of the N-terminal Domain of SARS-CoV-2 Spike Protein through Molecular Dynamics Simulation 期刊论文
ADVANCED THEORY AND SIMULATIONS, 2021, 页码: 13
作者:  Li, Yao;  Wang, Tong;  Zhang, Juanrong;  Shao, Bin;  Gong, Haipeng
收藏  |  浏览/下载:50/0  |  提交时间:2021/11/04
Structural insights into the activation of human calcium-sensing receptor 期刊论文
ELIFE, 2021, 卷号: 10, 页码: 24
作者:  Chen, Xiaochen;  Wang, Lu;  Cui, Qianqian;  Ding, Zhanyu;  Han, Li
收藏  |  浏览/下载:66/0  |  提交时间:2021/11/04
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15
作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua
收藏  |  浏览/下载:35/0  |  提交时间:2021/11/04
Structural basis for genome packaging, retention, and ejection in human cytomegalovirus 期刊论文
NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 14
作者:  Li, Zhihai;  Pang, Jingjing;  Dong, Lili;  Yu, Xuekui
收藏  |  浏览/下载:16/0  |  提交时间:2021/11/04
Structures of human mGlu2 and mGlu7 homo- and heterodimers 期刊论文
NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 589-+
作者:  Du, Juan;  Wang, Dejian;  Fan, Hongcheng;  Xu, Chanjuan;  Tai, Linhua
收藏  |  浏览/下载:26/0  |  提交时间:2021/08/17
Molecular Dynamics Simulations Reveal the Modulated Mechanism of STING Conformation 期刊论文
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2021, 页码: 15
作者:  Chen, Li;  Zhao, Shuang;  Zhu, Yanyan;  Liu, Yongsheng;  Li, Huiyu
收藏  |  浏览/下载:26/0  |  提交时间:2021/08/17


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