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Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:  Zhang, Huimin;  He, Jixiao;  Hu, Guang;  Zhu, Fei;  Jiang, Hao
收藏  |  浏览/下载:36/0  |  提交时间:2022/01/04
Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles 期刊论文
PHARMACEUTICAL RESEARCH, 2021, 页码: 22
作者:  Han, Sifei;  Mei, Lianghe;  Quach, Tim;  Porter, Chris;  Trevaskis, Natalie
收藏  |  浏览/下载:37/0  |  提交时间:2021/11/04
Design and Synthesis of Alkyl Phenols Inhibitors of Death Associated Apoptotic Protein Kinase 2 (DRAK2) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3204-3213
作者:  Zheng Zhang;  Dai Chengqiu;  Wu Honghong;  Li Jingya;  Nan Fajun
收藏  |  浏览/下载:20/0  |  提交时间:2021/11/04
Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca2+ ions and L-tryptophan 期刊论文
CELL RESEARCH, 2021, 页码: 12
作者:  Ling, Shenglong;  Shi, Pan;  Liu, Sanling;  Meng, Xianyu;  Zhou, Yingxin
收藏  |  浏览/下载:20/0  |  提交时间:2021/05/24
Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer 期刊论文
ADVANCED SCIENCE, 2021, 页码: 12
作者:  Sun, Fang;  Zhu, Qiurong;  Li, Tianliang;  Saeed, Madiha;  Xu, Zhiai
收藏  |  浏览/下载:46/0  |  提交时间:2021/05/24
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:  Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya
收藏  |  浏览/下载:35/0  |  提交时间:2021/05/24
Discovery of an Inhibitor for the TREK-1 Channel Targeting an Intermediate Transition State of Channel Gating 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 19, 页码: 10972-10983
作者:  Ma, Yuqin;  Luo, Qichao;  Fu, Jie;  Che, Yanxin;  Guo, Fei
收藏  |  浏览/下载:11/0  |  提交时间:2021/05/24
Lactoferrin-mediated macrophage targeting delivery and patchouli alcohol-based therapeutic strategy for inflammatory bowel diseases 期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 10, 页码: 1966-1976
作者:  Zhao, Yuge;  Yang, Yuting;  Zhang, Jiaxin;  Wang, Rong;  Cheng, Biyun
收藏  |  浏览/下载:26/0  |  提交时间:2020/12/24
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:  Xia, Zong-jun;  Ji, Yin-chun;  Sun, De-qiao;  Peng, Xia;  Gao, Ying-lei
收藏  |  浏览/下载:78/0  |  提交时间:2020/12/21
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi
收藏  |  浏览/下载:83/0  |  提交时间:2020/12/24


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