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科研机构
大连理工大学 [9]
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期刊论文 [9]
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2019 [1]
2017 [1]
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Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 147, 页码: 104387
作者:
Guo, Jianli
;
Wang, Qingling
;
Zhang, Yue
;
Sun, Wenhui
;
Zhang, Shuangzhe
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/12/02
Daidzein
Topotecan
Breast cancer
ER alpha
Drug resistance
Topoisomerase I
Quercetin exerts synergetic anti-cancer activity with 10-hydroxy camptothecin
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 109, 页码: 223-232
作者:
Tang, Qin
;
Ji, Fangling
;
Wang, Jingyun
;
Guo, Lianying
;
Li, Yachen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/03
Quercetin
10-Hydroxy camptothecin
Cancer therapeutic
Topoisomerase I
Cell cycle
Apoptosis
Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects
期刊论文
PHYTOMEDICINE, 2016, 卷号: 23, 页码: 1778-1786
作者:
Tang, Qin
;
Ji, Fangling
;
Sun, Wenhui
;
Wang, Jingyun
;
Guo, Jianli
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/09
Baicalein
10-hydroxy camptothecin
Anti-cancer
Topoisomerase I
p53
Apoptosis
Cyclane-aminol 10-hydroxycamptothecin analogs as novel DNA topoisomerase I inhibitors induce apoptosis selectively in tumor cells
期刊论文
ANTI-CANCER DRUGS, 2014, 卷号: 25, 页码: 614-623
作者:
Zhang, Shixuan
;
Geng, Tao
;
Jiang, Bo
;
Song, Ge
;
Ha, Lisha
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/09
cyclane-aminol 10-hydroxycamptothecin analogs 10-hydroxycamptothecin
intracellular hydrogen peroxide
PF1 topoisomerase I inhibitors
Microscopic modes and free energies for topoisomerase I-DNA covalent complex binding with non-camptothecin inhibitors by molecular docking and dynamics simulations
期刊论文
THEORETICAL CHEMISTRY ACCOUNTS, 2013, 卷号: 132, 页码: -
作者:
Wei, Ning-Ning
;
Hamza, Adel
;
Hao, Ce
;
Xiu, Zhilong
;
Zhan, Chang-Guo
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
Protein-ligand interaction
Binding affinity
Molecular dynamics simulation
Enzyme inhibitor
Pharmacokinetics, tissue distribution, and metabolism of novel DNA topoisomerase I inhibitor yuanhuacine in rabbit
期刊论文
XENOBIOTICA, 2009, 卷号: 39, 页码: 273-281
作者:
Zhang, S. X.
;
Yang, P. W.
;
Zhang, D. C.
;
Dong, W. Q.
;
Zhang, F. H.
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/24
Yuanhuacine
pharmacokinetics
metabolism
DNA topoisomerase I inhibitor
anti-cancer agent
Evaluation of poly(D,L-lactide-co-glycolide) microspheres for the lung-targeting of yuanhuacine, a novel DNA topoisomerase I inhibitor
期刊论文
JOURNAL OF DRUG TARGETING, 2009, 卷号: 17, 页码: 286-293
作者:
Zhang, Shixuan
;
Gao, Xiujuan
;
Shen, Kaihua
;
Yang, Puwen
;
Ju, Xiulan
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/24
PLGA microspheres
lung targeting
yuanhuacine
fluorescent spiropyran labeled
anticancer
Preparation of yuanhuacine and relative daphne diterpene esters from Daphne genkwa and structure-activity relationship of potent inhibitory activity against DNA topoisomerase I
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 卷号: 14, 页码: 3888-3895
作者:
Zhang Shixuan
;
Li Xiaona
;
Zhang Fenghong
;
Yang Puwen
;
Gao Xiujuan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
yuanhuacine
Daphne genkiva
daphne diterpene esters
inhibitory activity against DNA topoisomerase I
Novel synthetic isoquinolino[5,4-ab]phenazines: Inhibition toward topoisomerase I, antitumor and DNA photo-cleaving activities
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2005, 卷号: 13, 页码: 5909-5914
作者:
Yang, P
;
Yang, Q
;
Qian, XH
;
Cui, JN
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/02
phenazine naphthothiazole carboxamides
photocleavage
cytotoxicity
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