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科研机构
北京大学 [29]
内容类型
期刊论文 [25]
其他 [4]
发表日期
2017 [1]
2016 [2]
2015 [1]
2014 [2]
2013 [6]
2012 [1]
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共29条,第1-10条
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专题:北京大学
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Computational design of ligand-binding proteins
期刊论文
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2017
Yang, Wei
;
Lai, Luhua
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2017/12/03
ENZYME DESIGN
TRANSCRIPTION FACTORS
MOLECULAR-DYNAMICS
HIGH-AFFINITY
DOCKING
SPECIFICITY
SELECTIVITY
TARGETS
SITES
Yeast Two-Hybrid Screening for Proteins that Interact with the Extracellular Domain of Amyloid Precursor Protein
期刊论文
NEUROSCIENCE BULLETIN, 2016
Yu, You
;
Li, Yinan
;
Zhang, Yan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
Amyloid precursor protein
Alzheimer&apos
Yeast two-hybrid screening
Cell death
Pelizaeus-Merzbacher disease
PELIZAEUS-MERZBACHER DISEASE
APP-BINDING
SURFACE
FLRT3
CELL
OUTGROWTH
ADHESION
NEURONS
SYSTEM
FE65
s disease
Hubbard interactions in iron-based pnictides and chalcogenides: Slater parametrization, screening channels, and frequency dependence
期刊论文
PHYSICAL REVIEW B, 2016
van Roekeghem, Ambroise
;
Vaugier, Loig
;
Jiang, Hong
;
Biermann, Silke
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
MEAN-FIELD THEORY
STRONGLY CORRELATED SYSTEMS
ELECTRONIC-STRUCTURE
PHOTOEMISSION-SPECTROSCOPY
SUPERCONDUCTIVITY
SPECTRA
LIFEAS
FESE
GAP
Affinity purification in target identification: the specificity challenge
期刊论文
ARCHIVES OF PHARMACAL RESEARCH, 2015
Zheng, Wenlu
;
Li, Gang
;
Li, Xiaoyu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Target identification
Affinity purification
Small molecule
Phenotypic screening
Protein-ligand interaction
Specificity
PROTEIN-LIGAND INTERACTIONS
SMALL-MOLECULE PROBES
PHOTOAFFINITY CROSS-LINKING
BIOACTIVE SMALL MOLECULES
QUANTITATIVE CHEMICAL PROTEOMICS
HISTONE DEACETYLASE COMPLEXES
CARBOHYDRATE-BINDING PROTEINS
DIRECTED TOSYL CHEMISTRY
TAGGED TRIAZINE LIBRARY
A1 ADENOSINE RECEPTOR
Multivalent Photoaffinity Probe for Labeling Small Molecule Binding Proteins
期刊论文
生物共轭化学, 2014
Lo, Gang
;
Liu, Yu
;
Yu, Xuerong
;
Li, Xiaoyu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
DIRECTED TOSYL CHEMISTRY
COVALENT CROSS-LINKING
LIGAND-TARGET PAIRS
LIVING CELLS
IDENTIFICATION
DISCOVERY
RECEPTOR
COMPLEXES
LIBRARIES
3-TRIFLUOROMETHYL-3-PHENYLDIAZIRINE
Identification and functional validation of novel TRPV3 antagonists from natural product derivatives
其他
2014-01-01
张碧晨
;
张浩
;
李蒙
;
付宏征
;
王克威
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
permeable
bottleneck
gated
sensation
validation
physiology
clamp
screening
amplifier
throughput
permeable
bottleneck
gated
sensation
validation
physiology
clamp
screening
amplifier
throughput
Computational approaches for exploring the potential synergy and polypharmacology of Duhuo Jisheng Decoction in the therapy of osteoarthritis
期刊论文
molecular medicine reports, 2013
Zheng, Chun-Song
;
Xu, Xiao-Jie
;
Ye, Hong-Zhi
;
Wu, Guang-Wen
;
Li, Xi-Hai
;
Huang, Su-Ping
;
Liu, Xian-Xiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/16
Duhuo Jisheng Decoction
osteoarthritis
chemical space
virtual screening
network analysis
polypharmacology
TRADITIONAL CHINESE MEDICINE
DRUG DISCOVERY
NETWORK
VISUALIZATION
BIOLOGY
RISK
ACID
Network pharmacology-based prediction of the multi-target capabilities of the compounds in Taohong Siwu decoction, and their application in osteoarthritis
期刊论文
experimental and therapeutic medicine, 2013
Zheng, Chun-Song
;
Xu, Xiao-Jie
;
Ye, Hong-Zhi
;
Wu, Guang-Wen
;
Li, Xi-Hai
;
Xu, Hui-Feng
;
Liu, Xian-Xiang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2015/11/16
Taohong Siwu decoction
osteoarthritis
multi-target
network pharmacology
TRADITIONAL CHINESE MEDICINE
DRUG DISCOVERY
POLYPHARMACOLOGY
COMPONENTS
DATABASE
DISEASE
CELLS
MODEL
利用噬菌体展示技术筛选放射性标记肺癌靶肽YC11及其生物分布
其他
2013-01-01
梁坤
;
褚泰伟
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/10/24
噬菌体展示
靶肽
肺癌
生物分布
放射性标记
Phage display
Targeting peptide
Lung tumor
Biodistribution
Radiolabeling
Ligand-Free Palladium-Mediated Site-Specific Protein Labeling Inside Gram-Negative Bacterial Pathogens
期刊论文
journal of the american chemical society, 2013
Li, Jie
;
Lin, Shixian
;
Wang, Jie
;
Jia, Shang
;
Yang, Maiyun
;
Hao, Ziyang
;
Zhang, Xiaoyu
;
Chen, Peng R.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/10
AZIDE-ALKYNE CYCLOADDITION
UNNATURAL AMINO-ACIDS
PHOSPHOTHREONINE LYASE ACTIVITY
TRANSFER-RNA SYNTHETASE
DIELS-ALDER REACTIONS
CLICK CHEMISTRY
GENETIC-CODE
ESCHERICHIA-COLI
MAMMALIAN-CELLS
LIVING CELLS
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