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科研机构
上海药物研究所 [4]
西北高原生物研究所 [3]
过程工程研究所 [1]
海洋研究所 [1]
合肥物质科学研究院 [1]
内容类型
期刊论文 [10]
发表日期
2021 [10]
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Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8
作者:
Song, Zilan
;
Liu, Yuting
;
Xie, Chenghu
;
Tong, Xiankun
;
Wang, Xue
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Choroquine
Aminochloroquine
Antivirus
Anti-inflammatory
Cytokines
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:
Meng, Xiang-Dong
;
Gao, Li-Xin
;
Wang, Zhi-Jia
;
Feng, Bo
;
Zhang, Chun
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  |  
浏览/下载:31/0
  |  
提交时间:2021/12/01
2,5-diphenyl-1,3,4-oxadiazole derivatives
SHP2
Inhibitors
Structure-activity relationships (SAR)
Determination of chlorogenic acid in Eucommia ulmoides Oliver extracts by near-infrared spectroscopy
期刊论文
SPECTROSCOPY LETTERS, 2021
作者:
Oyebanji, Mayowa
;
Dong, Xuan
;
Zhang, Qianqian
;
Yao, Guohua
;
Huang, Qing
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  |  
浏览/下载:24/0
  |  
提交时间:2021/09/06
Chlorogenic acid
Eucommia ulmoides
near-infrared spectroscopy
quantitative analysis
Design, synthesis and pharmacological evaluation of tricyclic derivatives as selective RXFP4 agonists
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 17
作者:
Lin, Lin
;
Lin, Guangyao
;
Zhou, Qingtong
;
Bathgate, Ross A. D.
;
Gong, Grace Qun
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  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
Synthesis
Structure-activity relationship
Relaxin family peptide receptor 4
Selective agonist
Molecular docking
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:
Liu, Xiao
;
Jiang, Shuang
;
Kong, Linghui
;
Ye, Rongrong
;
Xiao, Li
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  |  
浏览/下载:114/0
  |  
提交时间:2021/05/24
Morphinans
arylacetamidyl substituent
kappa opioid receptor modulators
structure-activity relationships
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:
Zhang, Jiajia
;
Wu, Ning
;
Shi, Dayong
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  |  
浏览/下载:50/0
  |  
提交时间:2021/05/11
Signaling pathway
mammalian target of rapamycin
protein tyrosine phosphatase 1b
dipeptidase 4
cancer
diabetes
pharmacology
target compounds
Flavonoid compounds isolated from Tibetan herbs, binding to GABA(A) receptor with anxiolytic property
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 267
作者:
Liu, Zenggen
;
Silva, Joshua
;
Shao, Amy S.
;
Liang, Jing
;
Wallner, Martin
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  |  
浏览/下载:20/0
  |  
提交时间:2021/11/18
Flavonoids
Tibetan herbs
GABA(A) receptor
Structure-activity relationships
Anxiety
DeepDRK: a deep learning framework for drug repurposing through kernel-based multi-omics integration
期刊论文
BRIEFINGS IN BIOINFORMATICS, 2021, 卷号: 22, 期号: 5
作者:
Wang, Yongcui
;
Yang, Yingxi
;
Chen, Shilong
;
Wang, Jiguang
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  |  
浏览/下载:28/0
  |  
提交时间:2021/11/18
drug repurposing
multi-omics data sources
kernel-based data integration
machine learning
cancer precision medicine
Genus Ribes Linn. (Grossulariaceae): A comprehensive review of traditional uses, phytochemistry, pharmacology and clinical applications
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 276
作者:
Sun, Qing
;
Wang, Na
;
Xu, Wenhua
;
Zhou, Huakun
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/11/18
Ribes species
Grossulariaceae
Traditional uses
Phytochemistry
Pharmacology
Clinical application
Multi-Interactions in Ionic Liquids for Natural Product Extraction
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 1, 页码: 18
作者:
Zhang, Ying
;
Cao, Yingying
;
Wang, Hui
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/03/29
ionic liquids
multi-interactions
extraction
natural products
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