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科研机构
上海药物研究所 [8]
西北高原生物研究所 [2]
兰州理工大学 [1]
合肥物质科学研究院 [1]
烟台海岸带研究所 [1]
内容类型
期刊论文 [13]
发表日期
2021 [13]
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DHOK Exerts Anti-Cancer Effect Through Autophagy Inhibition in Colorectal Cancer
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 卷号: 9
作者:
Shu, Yuhan
;
Sun, Xin
;
Ye, Guiqin
;
Xu, Mengting
;
Wu, Zhipan
收藏
  |  
浏览/下载:155/0
  |  
提交时间:2022/02/14
DHOK
transcriptome sequencing
autophagy
colorectal cancer
mTOR pathway
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
Cong, Zhaotong
;
Zhou, Fulai
;
Zhang, Chao
;
Zou, Xinyu
;
Zhang, Huibing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:
Yuliantie, Elita
;
van der Velden, Wijnand J. C.
;
Labroska, Viktorija
;
Dai, Antao
;
Zhao, Fenghui
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
Glucose-dependent insulinotropic polypeptide receptor
G protein-coupled receptor
GPCR structure-function relationship
ERK
cAMP
Arrestin
Isolation and characterization of phellodendronoside A, a new isoquinoline alkaloid glycoside with anti-inflammatory activity from Phellodendron chinense Schneid
期刊论文
FITOTERAPIA, 2021, 卷号: 154
作者:
Si, Yanpo
;
Li, Xiaofei
;
Guo, Tao
;
Wei, Wenjun
;
Zhang, Jubao
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/17
Phellodendron chinense
Phellodendronoside A
Anti-inflammatory
MAPK pathway
Molecular docking
Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 218, 页码: 14
作者:
Yang, Xiangbo
;
Wang, Zhijia
;
Pei, Yuan
;
Song, Ning
;
Xu, Lei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/08/17
SHP2 degradation
Proteolysis targeting chimera (PROTAC)
Thalidomide-based heterobifunctional molecules
E3 ubiquitin ligase
CRBN
Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zan, Gui-ying
;
Sun, Xiang
;
Wang, Yu-jun
;
Liu, Rui
;
Wang, Chen-yao
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/08/17
depression
social defeat stress
amygdala
κ
opioid receptor
dynorphin
c-fos
ERK
norBNI
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Hemocyte extracellular traps of Manila clam Ruditapes philippinarum: Production characteristics and antibacterial effects
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 卷号: 116, 页码: 103953
作者:
Han, Yijing
;
Zhang, Qianqian
;
Yang, Dinglong
;
Zhao, Jianmin
;
Chen, Lizhu
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/12/01
Ruditapes philippinarum
Extracellular traps
Bactericidal effect
Reactive oxygen species
Glycolysis
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