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科研机构
上海药物研究所 [22]
内容类型
期刊论文 [22]
发表日期
2021 [22]
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共22条,第1-10条
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发表日期:2021
专题:上海药物研究所
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Synthesis and antiviral activity of 2 '-deoxy-6 '-substituted carbocyclic nucleosides
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 12
作者:
Xue, Haitao
;
Guo, Shuang
;
Hu, Tianwen
;
Wei, Daibao
;
Xie, Yuanchao
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/01/18
2 '-deoxy carbocyclic nucleoside
antiviral activity
hepatitis B virus
Mitsunobu reaction
NIR-II imaging of hepatocellular carcinoma based on a humanized anti-GPC3 antibody
期刊论文
RSC MEDICINAL CHEMISTRY, 2021, 页码: 8
作者:
Shi, Hui
;
Huttad, Lakshmi Vageesh
;
Tan, Mingdian
;
Liu, Hongguang
;
Chua, Mei-Sze
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/01/04
Synthesis and pharmacological evaluation of choroquine derivatives bearing long aminated side chains as antivirus and anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 8
作者:
Song, Zilan
;
Liu, Yuting
;
Xie, Chenghu
;
Tong, Xiankun
;
Wang, Xue
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2021/11/04
Choroquine
Aminochloroquine
Antivirus
Anti-inflammatory
Cytokines
Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer
期刊论文
ADVANCED MATERIALS, 2021, 页码: 12
作者:
Zhou, Fengqi
;
Gao, Jing
;
Tang, Yang
;
Zou, Zhifeng
;
Jiao, Shi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
antigen presentation
autophagy inhibition
immune resistance
immunotherapy
prodrug nanovesicles
Detachable Liposomes Combined Immunochemotherapy for Enhanced Triple-Negative Breast Cancer Treatment through Reprogramming of Tumor-Associated Macrophages
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 14, 页码: 6031-6041
作者:
Chen, Mingshu
;
Miao, Yunqiu
;
Qian, Kun
;
Zhou, Xin
;
Guo, Linmiao
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/11/04
Immunochemotherapy
triple-negative breast cancer
liposomes
tumor-associated macrophages
MMP2 response
Graphene nanoribbon-based supramolecular ensembles with dual-receptor targeting function for targeted photothermal tumor therapy
期刊论文
CHEMICAL SCIENCE, 2021, 页码: 9
作者:
Dou, Wei-Tao
;
Xu, Fugui
;
Xu, Chen-Xi
;
Gao, Jie
;
Ru, Hong-Bo
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2021/08/17
1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/ meta-substituted arenes
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 28, 页码: 5
作者:
Zhao, Jin-Xin
;
Chang, Yu-Xuan
;
He, Chi
;
Burke, Benjamin J.
;
Collins, Michael R.
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  |  
浏览/下载:17/0
  |  
提交时间:2021/11/04
synthesis
medicinal chemistry
bioisosteres
Affinity Mass Spectrometry-Based Fragment Screening Identified a New Negative Allosteric Modulator of the Adenosine A(2A) Receptor Targeting the Sodium Ion Pocket
期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 6, 页码: 991-1002
作者:
Lu, Yan
;
Liu, Hongyue
;
Yang, Dehua
;
Zhong, Li
;
Xin, Ye
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Deleterious mutation V369M in the mouse GCGR gene causes abnormal plasma amino acid levels indicative of a possible liver & ndash;alpha-cell axis
期刊论文
BIOSCIENCE REPORTS, 2021, 卷号: 41, 期号: 6, 页码: 12
作者:
Liu, Qiaofeng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/11/16
Rh(III)-catalyzed selective C7-H functionalization of indolines with 1,3-enynes enables access to six-membered 1,7-fused indolines
期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 72, 页码: 4
作者:
Shi, Yunkai
;
Chen, Chao
;
Yang, Yaxi
;
Zhou, Bing
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/08/17
C-H activation
1,7-Fused indoline
Enynes
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