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上海药物研究所 [5]
植物研究所 [4]
海洋研究所 [3]
合肥物质科学研究院 [2]
西双版纳热带植物园 [1]
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期刊论文 [20]
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2020 [20]
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Beyond Blocking: Engineering RNAi-Mediated Targeted Immune Checkpoint Nanoblocker Enables T-Cell-lndependent Cancer Treatment
期刊论文
ACS NANO, 2020, 卷号: 14
作者:
Han, Xiaoyan
;
Wang, Linlin
;
Li, Ting
;
Zhang, Jiahui
;
Zhang, Dailiang
收藏
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浏览/下载:54/0
  |  
提交时间:2021/03/15
immune checkpoint blockade
RNAi engineering
nanostructure
NSCLC
cancer immunotherapy
Engineering magnetosomes with chimeric membrane and hyaluronidase for efficient delivery of HIF-1 siRNA into deep hypoxic tumors
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2020, 卷号: 398, 页码: 12
作者:
Lyu, Chengliang
;
Lu, Guihong
;
Bao, Weier
;
Li, Feng
;
Wang, Shuang
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  |  
浏览/下载:40/0
  |  
提交时间:2020/10/30
Tumor-macrophage chimeric cell membrane
Hyaluronidase
Small interfering RNA delivery
Hypoxia
Hypoxia-inducible factor-1
Design, Synthesis, and Biological Activities of Novel Triazolothiadiazole Derivatives Linked with Amino Side Chain Containing Urea Group as DOT1L Inhibitors
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 8, 页码: 2450-2459
作者:
Liu Na
;
Guo Siqi
;
Liu Junfang
;
Chen Yantao
;
Xu Xiaoming
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  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
DOT1L inhibitor
triazolothiadiazole
triazolothiadiazine
nucleophilic substitution
CgMyD88s Serves as an Innate Immune System Plug During Ostreid Herpesvirus 1 Infection in the Pacific Oyster (Crassostrea gigas)
期刊论文
FRONTIERS IN IMMUNOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Tang, Xueying
;
Huang, Baoyu
;
Lin, Siheng
;
Wang, Wei
;
Zhang, Guofan
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  |  
浏览/下载:36/0
  |  
提交时间:2020/09/25
innate immunity
OsHV-1 mu Var
Crassostrea gigas
TLR
MyD88
3Scover: Identifying Safeguard TF from Cell Type-TF Specificity Network by an Extended Minimum Set Cover Model
期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 6, 页码: 31
作者:
Yuan, Qiuyue
;
Wang, Yong
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  |  
浏览/下载:34/0
  |  
提交时间:2020/09/23
Lamina feedback neurons regulate the bandpass property of the flicker-induced orientation response in Drosophila
期刊论文
JOURNAL OF NEUROCHEMISTRY, 2020, 页码: 17
作者:
Yuan, Deliang
;
Ji, Xiaoxiao
;
Hao, Shun
;
Gestrich, Julia Yvonne
;
Duan, Wenlan
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  |  
浏览/下载:48/0
  |  
提交时间:2020/08/24
bandpass response
Drosophila
feedback neurons
flicker-induced orientation
frequency
Structural Modifications of the Triazolo-thiadiazole Derivatives as DOT1L Inhibitors and Their Activities
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 5, 页码: 1345-1354
作者:
Xu Xiaoming
;
Guo Siqi
;
Zhang Jing
;
Chen Yantao
;
Kang Yaqing
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  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
DOT1L inhibitor
ttriazolo-thiadiazole
structural modification
hydrophobic substituent
structure-activity analysis
Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1
期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10, 页码: 16
作者:
Yan, Yi-lin
;
Huang, Zheng-nan
;
Zhu, Zhen
;
Cui, Yang-yan
;
Li, Mei-qian
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  |  
浏览/下载:84/0
  |  
提交时间:2020/12/24
ten-eleven translocation 1 (TET1)
DNA methylation
bladder cancer
vitamin C
adherens junction-associated protein 1 (AJAP1)
Transcriptome analysis reveals the regulation of the shrimp STAT on host chitin-binding domain containing proteins and energy metabolism process during WSSV infection
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2020, 卷号: 100, 页码: 345-357
作者:
Yang, Feifei
;
Li, Shihao
;
Xiang, Jianhai
;
Zhao, Xingming
;
Li, Fuhua
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  |  
浏览/下载:24/0
  |  
提交时间:2020/09/23
STAT
WSSV
Chitin binding
Glycolysis
Lipid metabolism
Litopenaeus vannamei
A proton-coupled organic cation antiporter is involved in the blood-brain barrier transport of Aconitum alkaloids
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 252, 页码: 9
作者:
Cong, Jiaojiao
;
Ruan, Yiling
;
Lyu, Qinglin
;
Qin, Xiaohui
;
Qi, Xinming
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  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Aconitum alkaloids
Blood-brain barrier
Proton-coupled organic cation antiporter
hCMEC/D3 cells
Drug transport
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