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上海药物研究所 [53]
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期刊论文 [154]
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Carbon ion combined with tigecycline inhibits lung cancer cell proliferation by inducing mitochondrial dysfunction
期刊论文
LIFE SCIENCES, 2020, 卷号: 263, 页码: 10
作者:
Yan, Junfang
;
Xie, Yi
;
Wang, Fang
;
Chen, Yuhong
;
Zhang, Jinhua
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/12/13
Mitochondrial dysfunction
Carbon ion radiation
Tigecycline
Mitochondrial translation
Akt/AMPK/mTOR pathway
Novel Carborane Compounds Based on Cyclooxygenase-2 Inhibitors for Effective Boron Neutron Capture Therapy of Tongue Squamous Cell Carcinoma
期刊论文
CHEMISTRYSELECT, 2020, 卷号: 5, 期号: 46, 页码: 14652-14660
作者:
Zhang, Taofeng
;
Du, Shaobo
;
Wang, Yu
;
Guo, Yanzhu
;
Yi, Yangman
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/12/13
Boron neutron capture therapy
Tongue squamous cell carcinoma
COX-2 inhibitors
Biological activity
Growth factors
Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells
期刊论文
CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24
作者:
Feng, Sisi
;
Wu, Jiaying
;
Qiu, Wei-Lin
;
Yang, Li
;
Deng, Xiaogang
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Dai, Meng-di
;
Wang, Yue-liang
;
Fan, Jun
;
Dai, Yang
;
Ji, Yin-chun
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  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
receptor tyrosine kinase
FGFR inhibitor
DW14383
antitumor activity
Protein Residues and a Novel Motif Involved in the Cellular Localization of CheZ in Azorhizobium caulinodans ORS571
期刊论文
FRONTIERS IN MICROBIOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Liu, Xiaolin
;
Liu, Yanan
;
Johnson, Kevin Scot
;
Dong, Xiaoyan
;
Xie, Zhihong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/06/07
chemotaxis
CheZ
cellular localization
Azorhizobium caulinodans
rhizobia
Harnessing Genomic Stress for Antitumor Immunity
期刊论文
ANTIOXIDANTS & REDOX SIGNALING, 2020, 页码: 23
作者:
Pu, Congying
;
Tao, Siyao
;
Xu, Jun
;
Huang, Min
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  |  
浏览/下载:20/0
  |  
提交时间:2021/05/24
genomic stress
cancer
genomic instability
antitumor immunity
DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways
期刊论文
EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8
作者:
Xu, Kai
;
Li, Bo
;
Zhang, Shujie
;
Hu, Fangyuan
;
Xu, Zhijian
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  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
DCZ3301
Apoptosis
PI3K/AKT pathway
ERK1/2 pathway
Choroid microvascular sprouting
Corneal neovascularization
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration
期刊论文
APPLIED MATERIALS TODAY, 2020, 卷号: 21
作者:
Xie, Bei
;
Chen, Mengting
;
Ding, Pinghui
;
Lei, Lei
;
Zhang, Xing
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  |  
浏览/下载:55/0
  |  
提交时间:2021/02/03
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