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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2020     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer 期刊论文 JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39 作者:  Ma, Liying;  Bian, Xing;  Lin, Wenchu 收藏  |  浏览/下载：38/0  |  提交时间：2020/11/30 SCLC  PI3K  HDAC  CUDC-907  PARP1  Olaparib  DSB repair  Combination treatment   Harnessing the targeting potential of differential radiobiological effects of photon versus particle radiation for cancer treatment 期刊论文 JOURNAL OF CELLULAR PHYSIOLOGY, 2020, 页码: 17 作者:  Zhang, Jinhua;  Si, Jing;  Gan, Lu;  Zhou, Rong;  Guo, Menghuan 收藏  |  浏览/下载：26/0  |  提交时间：2022/01/12 DNA damage  DNA repair  particle therapy  photon therapy  radiosensitizer   Phase I dose-escalation and expansion study of PARP inhibitor, fluzoparib (SHR3162), in patients with advanced solid tumors 期刊论文 CHINESE JOURNAL OF CANCER RESEARCH, 2020, 卷号: 32, 期号: 3, 页码: 370-+ 作者:  Li, Huiping;  Liu, Rongrui;  Shao, Bin;  Ran, Ran;  Song, Guohong 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24 Phase I  PARP inhibitor (fluzoparib)  solid tumor  pharmacokinetics  safety  antitumor activity   BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis 期刊论文 THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12 作者:  Li, Guang;  Zheng, Yan-Hua;  Xu, Li;  Feng, Juan;  Tang, Hai-Long 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/24 apoptosis  BRD4 inhibitor  G1 phase cell cycle checkpoint  multiple myeloma   BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245 作者:  Guo, Chuanlong;  Zhang, Fan;  Wu, Xiaochen;  Yu, Xuemin;  Wu, Xianggen 收藏  |  浏览/下载：32/0  |  提交时间：2020/09/23 PARP-1 inhibitor  DNA double-strand breaks  HCC-1937  In vivo  Apoptosis   Terphenyllin Suppresses Orthotopic Pancreatic Tumor Growth and Prevents Metastasis in Mice 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11 作者:  Zhang, Jia;  Wang, Weiyi;  Zhou, Yuan;  Yang, Jing;  Xu, Jingli 收藏  |  浏览/下载：25/0  |  提交时间：2020/11/26 terphenyllin  pancreatic cancer  metastasis  Bax  Bcl-2  Puma   Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422 作者:  Lai, Meng-zhen;  Song, Pei-ran;  Dou, Dou;  Diao, Yan-yan;  Tong, Lin-jiang 收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01 B cell receptor  Bruton's tyrosine kinase  ibrutinib  small-molecule inhibitor  B cell malignancies   discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors 期刊论文 actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415 作者:  Lai Mengzhen;  Song Peiran;  Dou Dou;  Diao Yanyan;  Tong Linjiang 收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01 B cell receptor  Bruton’s tyrosine kinase  ibrutinib  small-molecule inhibitor  B cell malignancies   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong 收藏  |  浏览/下载：11/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance   Novel mutations in BRCA2 intron 11 and overexpression of COX-2 and BIRC3 mediate cellular resistance to PARP inhibitors 期刊论文 AMERICAN JOURNAL OF CANCER RESEARCH, 2020, 卷号: 10, 期号: 9, 页码: 2813-+ 作者:  Chen, Hua-Dong;  Guo, Ne;  Song, Shan-Shan;  Chen, Chuan-Huizi;  Miao, Ze-Hong 收藏  |  浏览/下载：51/0  |  提交时间：2020/12/24 PARP inhibitors resistance  BRCA2  COX-2  BIRC3  apoptotic resistance