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浏览/检索结果: 共44条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文 CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280 作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong 收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24 SPOP  Protein‐  protein interaction  Clear cell Renal Cell Carcinomas  Crystal structure  Peptide inhibitor   Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway 期刊论文 SCIENTIFIC REPORTS, 2020, 卷号: 10, 期号: 1, 页码: 13 作者:  Xue, Yaru;  Deng, Qiangqiang;  Zhang, Qingli;  Ma, Zhenghua;  Chen, Binfan 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways 期刊论文 EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8 作者:  Xu, Kai;  Li, Bo;  Zhang, Shujie;  Hu, Fangyuan;  Xu, Zhijian 收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24 DCZ3301  Apoptosis  PI3K/AKT pathway  ERK1/2 pathway  Choroid microvascular sprouting  Corneal neovascularization   Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway 期刊论文 ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298 作者:  Ding, Chunyong;  Song, Zilan;  Shen, Ancheng;  Chen, Tingting;  Zhang, Ao 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 Immunotherapy  Anti-tumor  cGAS  STING  TBK1  Small molecule modulators   Cinnamtannin D1 Protects Pancreatic beta-Cells from Glucolipotoxicity-Induced Apoptosis by Enhancement of Autophagy In Vitro and In Vivo 期刊论文 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 卷号: 68, 期号: 45, 页码: 12617-12630 作者:  Wang, Xin-Yi;  Zhu, Bo-Rong;  Jia, Qi;  Li, Yi-Ming;  Wang, Ting 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 cinnamtannin D1  pancreatic beta-cells  autophagy  apoptosis  type 2 diabetes   Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway 期刊论文 MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15 作者:  Liu, Siwen;  Huang, Suling;  Wu, Xingde;  Feng, Ying;  Shen, Yu 收藏  |  浏览/下载：55/0  |  提交时间：2020/12/24 Salt-inducible kinase 1  Phanginin A  Phosphodiesterase 4  Gluconeogenesis  cAMP   Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice 期刊论文 ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56 作者:  Xu, Xiaoju;  Xu, Xu;  Hao, Yanping;  Zhu, Xialin;  Lu, Jian 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Comprehensive analysis of transcriptomics and metabolomics to understand triptolide-induced liver injury in mice 期刊论文 TOXICOLOGY LETTERS, 2020, 卷号: 333, 页码: 290-302 作者:  Zhao, Jie;  Xie, Cen;  Wang, Kanglong;  Takahashi, Shogo;  Krausz, Kristopher W. 收藏  |  浏览/下载：49/0  |  提交时间：2020/12/21 Triptolide  Transcriptomics  Metabolomics  Apoptosis  Acylcarnitine   Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system 期刊论文 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 5, 页码: 466-472 作者:  Dong, Ying;  Li, Xiao-Rong;  Li, Jia;  Zang, Yi;  Li, Xin 收藏  |  浏览/下载：107/0  |  提交时间：2020/12/21 Nitric oxide modulator  Drug screen  Fluorescence imaging  Microenvironment  Endothelial cell   A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters 期刊论文 TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14 作者:  Wang, Ying;  Zhu, Yao;  Niu, Junxing;  Deng, Qiangqiang;  Guo, Shimeng 收藏  |  浏览/下载：60/0  |  提交时间：2020/12/21 Bile acid analog  NASH  TGR5  Cd36  AMPK alpha