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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149 作者:  Pan, Lijia;  Nie, Litong;  Yao, Sheng;  Bi, Aiwei;  Ye, Yang 收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 neuroblastoma  bufalin  chemical proteomics  ETC  mitochondria   Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7 作者:  Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan 收藏  |  浏览/下载：21/0  |  提交时间：2021/05/24 Drug design  CBP  Bromodomain  Inhibitor  Acute myeloid leukemia   Unveiling conformational dynamics changes of H-Ras induced by mutations based on accelerated molecular dynamics 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2020, 卷号: 22, 期号: 37, 页码: 21238-21250 作者:  Chen, Jianzhong;  Wang, Wei;  Pang, Laixue;  Zhu, Weiliang 收藏  |  浏览/下载：27/0  |  提交时间：2020/12/21 Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system 期刊论文 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 5, 页码: 466-472 作者:  Dong, Ying;  Li, Xiao-Rong;  Li, Jia;  Zang, Yi;  Li, Xin 收藏  |  浏览/下载：107/0  |  提交时间：2020/12/21 Nitric oxide modulator  Drug screen  Fluorescence imaging  Microenvironment  Endothelial cell   The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5 作者:  Huang, Ying;  Ru, Hong-bo;  Bao, Bin;  Yu, Jia-hui;  Li, Jia 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24 HDAC  Probe  NIR  Tumor imaging   Discovery of novel USP8 inhibitors via Ubiquitin-Rho-110 fluorometric assay based high throughput screening 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 9 作者:  Han, Jie;  Tian, Yucheng;  Yu, Liang;  Zhang, Qilin;  Xu, Xi 收藏  |  浏览/下载：61/0  |  提交时间：2020/12/24 Ubiquitination  High throughput screening  Drug discovery  USP8   Mechanochemical Activation of Class-B G-Protein-Coupled Receptor upon Peptide-Ligand Binding 期刊论文 NANO LETTERS, 2020, 卷号: 20, 期号: 7, 页码: 5575-5582 作者:  Lo Giudice, Cristina;  Zhang, Haonan;  Wu, Beili;  Alsteens, David 收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24 Atomic force microscopy  single-molecule force spectroscopy  human glucagon receptor  G-protein-coupled receptors  mechanotransduction   Selective N-glycan editing on living cell surfaces to probe glycoconjugate function 期刊论文 NATURE CHEMICAL BIOLOGY, 2020, 页码: 15 作者:  Tang, Feng;  Zhou, Mang;  Qin, Ken;  Shi, Wei;  Yashinov, Ansor 收藏  |  浏览/下载：72/0  |  提交时间：2020/07/01 Lead discovery, chemical optimization, and biological evaluation studies of novel histone methyltransferase SET7 small-molecule inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 9, 页码: 10 作者:  Hou, Zeng;  Min, Wenjian;  Zhang, Rukang;  Niu, Ao;  Li, Yuanqing 收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01 Histone methylation  SET7  Small-molecule inhibitor  Virtual screening  Molecular probe   Optimized HSP90 mediated fluorescent probes for cancer-specific bioimaging 期刊论文 JOURNAL OF MATERIALS CHEMISTRY B, 2020, 卷号: 8, 期号: 9, 页码: 1878-1896 作者:  Zhu, Shulei;  Li, Yalei;  Huang, Yushu;  Zhang, Minmin;  Gu, Xiaofan 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01