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浏览/检索结果: 共35条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文 CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280 作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong 收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24 SPOP  Protein‐  protein interaction  Clear cell Renal Cell Carcinomas  Crystal structure  Peptide inhibitor   DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun 收藏  |  浏览/下载：32/0  |  提交时间：2021/05/24 receptor tyrosine kinase  FGFR inhibitor  DW14383  antitumor activity   Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase 期刊论文 ACS INFECTIOUS DISEASES, 2020, 卷号: 6, 期号: 11, 页码: 2994-3003 作者:  Butler, Joshua H.;  Baptista, Rodrigo P.;  Valenciano, Ana L.;  Zhou, Bin;  Kissinger, Jessica C. 收藏  |  浏览/下载：14/0  |  提交时间：2021/05/24 Plasmodium  PfPARE  structure-resistance relationship study  Malaria Box  Pathogen Box  lindenane sesquiterpenoid dimers   Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11 作者:  Wang, Yuwei;  Tang, Shuai;  Lai, Huanling;  Jin, Ruyi;  Long, Xu 收藏  |  浏览/下载：48/0  |  提交时间：2020/12/24 IDH1  gliomas  molecular docking  virtual screening  docking-based virtual screening   Mutation-induced remodeling of the BfmRS two-component system in Pseudomonas aeruginosa clinical isolates 期刊论文 SCIENCE SIGNALING, 2020, 卷号: 13, 期号: 656, 页码: 21 作者:  Cao, Qiao;  Yang, Nana;  Wang, Yanhui;  Xu, Chenchen;  Zhang, Xue 收藏  |  浏览/下载：131/0  |  提交时间：2020/12/24 Structural basis for activation of the growth hormone-releasing hormone receptor 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 10 作者:  Zhou, Fulai;  Zhang, Huibing;  Cong, Zhaotong;  Zhao, Li-Hua;  Zhou, Qingtong 收藏  |  浏览/下载：23/0  |  提交时间：2020/12/21 Unveiling conformational dynamics changes of H-Ras induced by mutations based on accelerated molecular dynamics 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2020, 卷号: 22, 期号: 37, 页码: 21238-21250 作者:  Chen, Jianzhong;  Wang, Wei;  Pang, Laixue;  Zhu, Weiliang 收藏  |  浏览/下载：26/0  |  提交时间：2020/12/21 Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19 作者:  Che, Jinxin;  Huang, Feng;  Zhang, Mengmeng;  Xu, Gaoya;  Qu, Bingxue 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/21 Metabolic pathways  Isocitrate dehydrogenase 2  Conformational restriction  Macrocyclic derivatives  Inhibitors   SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways 期刊论文 CANCER CELL, 2020, 卷号: 38, 期号: 3, 页码: 350-+ 作者:  Yuan, Huairui;  Han, Ying;  Wang, Xuege;  Li, Ni;  Liu, Qiuli 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24