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科研机构
上海药物研究所 [31]
内容类型
期刊论文 [31]
发表日期
2020 [31]
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共31条,第1-10条
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发表日期:2020
专题:上海药物研究所
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:
Wang, Zhen
;
Zhang, Hao
;
Chen, Baoen
;
Ouyang, Sisheng
;
Zheng, Tong
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2021/05/24
SPOP
Protein‐
protein interaction
Clear cell Renal Cell Carcinomas
Crystal structure
Peptide inhibitor
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor
期刊论文
CELL RESEARCH, 2020, 页码: 11
作者:
Sun, Wen
;
Chen, Li-Nan
;
Zhou, Qingtong
;
Zhao, Li-Hua
;
Yang, Dehua
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
In situ observation of Li2O-Al2O3-SiO2 glass crystallization process and kinetics analysis
期刊论文
JOURNAL OF CRYSTAL GROWTH, 2020, 卷号: 547, 页码: 6
作者:
Li, Huidong
;
Yang, Liping
;
Cao, ChengCheng
;
Tao, Ye
;
Zhong, Qiu
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2020/12/21
Crystallites
Nucleation
Confocal laser scanning microscopy
Crystal growth
Glass
GPR91, a critical signaling mechanism in modulating pathophysiologic processes in chronic illnesses
期刊论文
FASEB JOURNAL, 2020, 页码: 15
作者:
Li, Xinyi
;
Xie, Li
;
Qu, Xiangli
;
Zhao, Bangyi
;
Fu, Wei
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
G protein-coupled receptor
innate immunity
metabolic regulation
succinate
SUCNR1
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Identification of Highly Selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Inhibitors by a Covalent Fragment-Based Approach
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 13, 页码: 7052-7065
作者:
Huang, Fubao
;
Hu, Hangchen
;
Wang, Kai
;
Peng, Chengyuan
;
Xu, Wenwei
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Natural product piperine alleviates experimental allergic encephalomyelitis in mice by targeting dihydroorotate dehydrogenase
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020, 卷号: 177, 页码: 15
作者:
Liu, Zehui
;
Hu, Qian
;
Wang, Wanyan
;
Lu, Sisi
;
Wu, Dang
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/12/24
Multiple sclerosis
DHODH
Piperine
Natural product
In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 6, 页码: 3265-3276
作者:
Zhao, Wenfeng
;
Xiong, Muya
;
Yuan, Xiaojing
;
Li, Minjun
;
Sun, Hongbin
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/12/24
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