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浏览/检索结果: 共38条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文 CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280 作者:  Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong 收藏  |  浏览/下载：124/0  |  提交时间：2021/05/24 SPOP  Protein‐  protein interaction  Clear cell Renal Cell Carcinomas  Crystal structure  Peptide inhibitor   DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Dai, Meng-di;  Wang, Yue-liang;  Fan, Jun;  Dai, Yang;  Ji, Yin-chun 收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24 receptor tyrosine kinase  FGFR inhibitor  DW14383  antitumor activity   DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways 期刊论文 EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8 作者:  Xu, Kai;  Li, Bo;  Zhang, Shujie;  Hu, Fangyuan;  Xu, Zhijian 收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24 DCZ3301  Apoptosis  PI3K/AKT pathway  ERK1/2 pathway  Choroid microvascular sprouting  Corneal neovascularization   Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin 期刊论文 STEROIDS, 2020, 卷号: 164, 页码: 11 作者:  Zhou, Yang;  Hou, Jinjun;  Long, Huali;  Zhang, Zijia;  Lei, Min 收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 Cardiac glycosides  Cinobufagin  Natural product  Cytotoxicity  Antiproliferative activities   Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 卷号: 46, 期号: 6, 页码: 2137-2149 作者:  Pan, Lijia;  Nie, Litong;  Yao, Sheng;  Bi, Aiwei;  Ye, Yang 收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 neuroblastoma  bufalin  chemical proteomics  ETC  mitochondria   The Active Constituent From Gynostemma Pentaphyllum Prevents Liver Fibrosis Through Regulation of the TGF-beta 1/NDRG2/MAPK Axis 期刊论文 FRONTIERS IN GENETICS, 2020, 卷号: 11, 页码: 11 作者:  Huang, Hui;  Wang, Kuifeng;  Liu, Qian;  Ji, Feihong;  Zhou, Hu 收藏  |  浏览/下载：33/0  |  提交时间：2020/12/24 HSC  TGF-β  1  liver fibrosis  quantitative proteomics  NDRG2   A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 162, 页码: 107-115 作者:  Bian, Youcheng;  Zeng, Hui;  Tao, Hong;  Huang, Lulin;  Du, Zhenyun 收藏  |  浏览/下载：15/0  |  提交时间：2020/12/24 Polygala tenuifolia  Pectin  Pancreatic cancer  Apoptosis  Autophagy   Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery 期刊论文 BIOMATERIALS, 2020, 卷号: 255, 页码: 12 作者:  Chen, Binfan;  Gao, Ang;  Tu, Bin;  Wang, Yonghui;  Yu, Xiaolu 收藏  |  浏览/下载：30/0  |  提交时间：2020/12/24 Tumor-associated macrophage  Glycolysis  mTOR  Angiogenesis  Tumor immune microenvironment  Liposome   SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7 作者:  Xia, Zong-jun;  Ji, Yin-chun;  Sun, De-qiao;  Peng, Xia;  Gao, Ying-lei 收藏  |  浏览/下载：78/0  |  提交时间：2020/12/21 ROS1 kinase  ROS1 inhibitor  SAF-189s  lorlatinib  crizotinib resistance  G2032R mutant  NSCLC   Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia