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Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway 期刊论文
2019, 卷号: 40, 期号: 1, 页码: 13-25
作者:  Chu, Shi-feng;  Zhang, Zhao;  Zhou, Xin;  He, Wen-bin;  Chen, Chen
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway 期刊论文
Acta Pharmacologica Sinica, 2019, 卷号: 40, 期号: 1, 页码: 13-25
作者:  Chu, Shi-feng;  Zhang, Zhao;  Zhou, Xin;  He, Wen-bin;  Chen, Chen
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/27
NK cells in cerebral ischemia 期刊论文
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, 卷号: 109, 页码: 547-554
作者:  Chen, Chen;  Ai, Qi-Di;  Chu, Shi-Feng;  Zhang, Zhao;  Chen, Nai-Hong*
收藏  |  浏览/下载:36/0  |  提交时间:2019/12/27
tPA  tissue plasminogen activator  IS  ischemic stroke  BBB  blood-brain barrier  IFN-γ  interferon-γ  pMCAO  permanent middle cerebral artery occlusion  tMCAO  transient middle cerebral artery occlusion  CX3CR1  CX3CL1 receptor  CNS  central nervous system  AchE  acetylcholine esterase  CFSE  arboxyfluorescein diacetate succinimidyl ester  HI  hypoxic ischemia  MCAO IP-10  interferon-inducible protein-10  IL  interleukin  GFAP  glial fibrillary acidic protein  tg  transgenic  WT  wild-type  APC  antigen presenting cell  SAI  stroke-associated infection  STAT3  signal transducer and activator of transcription-3  HPA  hypothalamic-pituitary-adrenal  cSVD  cerebral small vessel disease  SHR  spontaneously hypertensive rat  CSF  cerebrospinal fluid  aSAH  aneurysmal subarachnoid hemorrhage  DCI  delayed cerebral ischemia  MRI  magnetic resonance imaging  CT  computed tomography  EVs  extracellular vesicles  MSC  mesenchymal stem cell  MNCs  bone marrow-derived mononuclear cells  CpG-ODN  cytosine-guanine oligodideoxynucleotide  TLR9  toll-like receptor 9  TNF  tumor necrosis factor  NK cells  Cerebral ischemia  Inflammation  Immunodpression  Infection  


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