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Conformation of the Macrocyclic Drug Lorlatinib in Polar and Nonpolar Environments: A MD Simulation and NMR Study 期刊论文
ACS OMEGA, 2019, 卷号: 4, 期号: 26, 页码: 22245-22250
作者:  Peng, Cheng;  Atilaw, Yoseph;  Wang, Jinan;  Xu, Zhijian;  Poongavanam, Vasanthanathan
收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01
Common activation mechanism of class A GPCRs 期刊论文
ELIFE, 2019, 卷号: 8, 页码: 31
作者:  Zhou, Qingtong;  Yang, Dehua;  Wu, Meng;  Guo, Yu;  Guo, Wangjing
收藏  |  浏览/下载：66/0  |  提交时间：2020/07/01
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li
收藏  |  浏览/下载：14/0  |  提交时间：2020/03/18
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease 期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:  Zhang, Yu;  Wu, Qimei;  Zhang, Lei;  Wang, Qing;  Yang, Zexian
收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Wang, Yi;  Song, Kun
收藏  |  浏览/下载：75/0  |  提交时间：2020/07/01
Associating lncRNAs with small molecules via bilevel optimization reveals cancer-related lncRNAs 期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2019, 卷号: 15, 期号: 12, 页码: 20
作者:  Wang, Yongcui;  Chen, Shilong;  Chen, Luonan;  Wang, Yong
收藏  |  浏览/下载：54/0  |  提交时间：2020/05/24
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
Acid-activatable Polymeric Drug Delivery Systems for Cancer Therapy 期刊论文
ACTA POLYMERICA SINICA, 2019, 卷号: 50, 期号: 11, 页码: 1156-1166
作者:  Gao, Jing;  Wang, Wei-qi;  Yu, Hai-jun
收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01
Dynamic modifications of biomacromolecules: mechanism and chemical interventions 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1459-1471
作者:  Wang, Chu;  Zou, Peng;  Yang, Caiguang;  Liu, Lei;  Cheng, Liang
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Tyrosine Kinase 2 (TYK2) Allosteric Inhibitors To Treat Autoimmune Diseases 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 20, 页码: 8951-8952
作者:  Chang, Yu;  Xu, Shilin;  Ding, Ke
收藏  |  浏览/下载：17/0  |  提交时间：2020/07/01

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