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科研机构
上海药物研究所 [12]
湖南大学 [3]
武汉物理与数学研究所 [1]
四川大学 [1]
内容类型
期刊论文 [17]
发表日期
2019 [17]
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Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests
期刊论文
CHINESE MEDICINE, 2019, 卷号: 14, 期号: 1, 页码: 11
作者:
Zhong, Ming
;
Tian, Xiaoting
;
Chen, Shuoji
;
Chen, Mingcang
;
Guo, Ziqiong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Baihe-Zhimu decoction
Antidepressant
Timosaponin BII
Timosaponin BIII
Drug discovery
High degree of pharmacokinetic compatibility exists between the five-herb medicine XueBiJing and antibiotics comedicated in sepsis care
期刊论文
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 5, 页码: 1035-1049
作者:
Li, Jian
;
Olaleye, Olajide E.
;
Yu, Xuan
;
Jia, Weiwei
;
Yang, Junling
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
XueBiJing
Antibiotic
Combination drug therapy
Sepsis
Pharmacokinetic compatibility
Herb-drug interaction
Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 8, 页码: 843-853
作者:
Li, Xiuli
;
Sun, Jingchao
;
Guo, Zitao
;
Zhong, Dafang
;
Chen, Xiaoyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysis
期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2019, 卷号: 84, 期号: 2, 页码: 373-382
作者:
Petain, Aurelie
;
Zhong, Dafang
;
Chen, Xiaoyan
;
Li, Zhang
;
Shao Zhimin
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Vinorelbine
Non-small-cell lung cancer
Breast cancer
China
Pharmacokinetics
Mechanism of Reductive Metabolism and Chiral Inversion of Proton Pump Inhibitors
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 6, 页码: 657-664
作者:
Tang, Chongzhuang
;
Chen, Zhaoqiang
;
Dai, Xiaojian
;
Zhu, Weiliang
;
Zhong, Dafang
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 4, 页码: 364-376
作者:
Wang, Fengling
;
Wu, Yifan
;
Zhang, Jiwen
;
Wang, Huihui
;
Xie, Xiaoting
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/07/01
Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation
期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 2, 页码: 86-93
作者:
Patterson, Andrew D.
;
Anitha, Mallappa
;
Zhang, Jingtao
;
Koo, Imhoi
;
Nichols, Robert G.
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  |  
浏览/下载:52/0
  |  
提交时间:2019/06/24
Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:
Tian, Xiaoting
;
Liu, Fang
;
Li, Zhixiong
;
Lin, Yunfei
;
Liu, Huan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
berberine
timosaponin B2
diabetes
combination treatments
drug-drug interaction
metabolites
hepatic metabolism
intestinal absorption
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:
Li, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 Are Responsible for Tertiary Oxidations of Deoxycholate Species.
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2019
作者:
Zhang Jian
;
Gao Ling-Zhi
;
Chen Yu-Jie
;
Zhu Ping-Ping
;
Yin Shan-Shan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/02/25
UPLC
bile
acid
metabolism/transport
cytochrome
P450
mass
spectrometry/MS
metabolomics
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