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浏览/检索结果: 共44条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 DZ2002 ameliorates fibrosis, inflammation, and vasculopathy in experimental systemic sclerosis models 期刊论文 ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 期号: 1, 页码: 15 作者:  Zhang, Zongwang;  Wu, Yanwei;  Wu, Bing;  Qi, Qing;  Li, Heng 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Systemic sclerosis  SAHH inhibitor  Fibrosis  Inflammation  Vasculopathy  TGF-beta   Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15 作者:  Lu, Wenchao;  Wang, Jun;  Li, Yong;  Tao, Hongru;  Xiong, Huan 收藏  |  浏览/下载：94/0  |  提交时间：2020/07/01 Hippo pathway  TEAD transcription factor  Covalent inhibitor  Palmitoylation inhibitor   RepSox, a small molecule inhibitor of the TGF beta receptor, induces brown adipogenesis and browning of white adipocytes 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1523-1531 作者:  Tu, Wan-zhi;  Fu, Yan-bin;  Xie, Xin 收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01 RepSox  brown adipogenesis  TGF-beta receptor  TGF-beta inhibitor  adipocyte  differentiation   3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586 作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang 收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 JAK/STAT  3-deoxy-2 beta,16-dihydroxynagilactone E  tyrosine kinase inhibitor  allosteric inhibitor  cancer   Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas 期刊论文 BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13 作者:  Zhang, Qing;  Liu, Jian-He;  Liu, Jing-Li;  Qi, Chun-Ting;  Yan, Lei 收藏  |  浏览/下载：60/0  |  提交时间：2020/07/01 Receptor tyrosine kinases (RTKs)  Activation and function  Clear cell renal cell carcinomas (ccRCCs)  Targeted therapy  PDGFR beta  Stroma cells   Neuroprotective Effect of Natural Alkaloid Fangchinoline Against Oxidative Glutamate Toxicity: Involvement of Keap1-Nrf2 Axis Regulation 期刊论文 CELLULAR AND MOLECULAR NEUROBIOLOGY, 2019, 卷号: 39, 期号: 8, 页码: 1177-1186 作者:  Bao, Fengxia;  Tao, Lingxue;  Zhang, Haiyan 收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01 Fangchinoline  Keap1  Nrf2  Oxidative stress   PD-L1 expression levels on tumor cells affect their immunosuppressive activity 期刊论文 ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407 作者:  Zheng, Yang;  Fang, You-Chen;  Li, Jing 收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 programmed cell death 1  programmed death-ligand 1  co-culture  immunosuppression  signaling pathway   Long noncoding RNA LINC00336 inhibits ferroptosis in lung cancer by functioning as a competing endogenous RNA 期刊论文 CELL DEATH AND DIFFERENTIATION, 2019, 卷号: 26, 期号: 11, 页码: 2329-2343 作者:  Wang, Min;  Mao, Chao;  Ouyang, Lianlian;  Liu, Yating;  Lai, Weiwei 收藏  |  浏览/下载：36/0  |  提交时间：2020/07/01 Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291 作者:  Fan, Lei;  Qiu, Xiao-xia;  Zhu, Zhi-yuan;  Lv, Jian-lu;  Lu, Jian 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 Alzheimer's disease  nitazoxanide  autophagy  inflammation  APP/PS1 transgenic mice   SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文 CANCER SCIENCE, 2019, 页码: 11 作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun 收藏  |  浏览/下载：21/0  |  提交时间：2020/07/01 AZD9291  c-Met ADC  c-Met overexpression  resistance  SHR-A1403