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浏览/检索结果: 共24条，第1-10条 帮助 限定条件 发表日期：2019    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer 期刊论文 CELL METABOLISM, 2019, 卷号: 30, 期号: 6, 页码: 1107-+ 作者:  Huang, Ke;  Liang, Qian;  Zhou, Ye;  Jiang, Lu-lu;  Gu, Wei-ming 收藏  |  浏览/下载：77/0  |  提交时间：2020/07/01 3-Deoxy-2 beta,16-dihydroxynagilactone E, a natural compound from Podocarpus nagi, preferentially inhibits JAK2/STAT3 signaling by allosterically interacting with the regulatory domain of JAK2 and induces apoptosis of cancer cells 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1578-1586 作者:  Shan, Hui;  Yao, Sheng;  Ye, Yang;  Yu, Qiang 收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 JAK/STAT  3-deoxy-2 beta,16-dihydroxynagilactone E  tyrosine kinase inhibitor  allosteric inhibitor  cancer   PD-L1 expression levels on tumor cells affect their immunosuppressive activity 期刊论文 ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407 作者:  Zheng, Yang;  Fang, You-Chen;  Li, Jing 收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01 programmed cell death 1  programmed death-ligand 1  co-culture  immunosuppression  signaling pathway   Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma 期刊论文 CELL, 2019, 卷号: 179, 期号: 2, 页码: 561-+ 作者:  Gao, Qiang;  Zhu, Hongwen;  Dong, Liangqing;  Shi, Weiwei;  Chen, Ran 收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291 作者:  Fan, Lei;  Qiu, Xiao-xia;  Zhu, Zhi-yuan;  Lv, Jian-lu;  Lu, Jian 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 Alzheimer's disease  nitazoxanide  autophagy  inflammation  APP/PS1 transgenic mice   Ligand-induced activation of ERK1/2 signaling by constitutively active G(s)-coupled 5-HT receptors 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1157-1167 作者:  Liu, Ping;  Yin, Yu-ling;  Wang, Ting;  Hou, Li;  Wang, Xiao-xi 收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 5-HT4R  5-HT6R  5-HT7AR  5-HT  ERK1/2  G(s)  beta-arrestin  Fyn  Src   Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1193-1204 作者:  Zhou, Ting-ting;  Zhao, Tong;  Ma, Fei;  Zhang, Yi-nan;  Jiang, Jing 收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 type 2 diabetes mellitus  hepatic gluconeogenesis  AMPK signaling pathway  (E)-3-(2-(quinoline-4-yl)vinyl)-1H-indol-6-ol (QVO)  4-[2-(1H-indol-3-yl)vinyl]quinoline (IVQ)  prodrug   Identification of a new inhibitor of KRAS-PDE delta interaction targeting KRAS mutant nonsmall cell lung cancer 期刊论文 INTERNATIONAL JOURNAL OF CANCER, 2019, 卷号: 145, 期号: 5, 页码: 1334-1345 作者:  Leung, Elaine Lai-Han;  Luo, Lian Xiang;  Li, Ying;  Liu, Zhong-Qiu;  Li, Lan Lan 收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01 SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC 期刊论文 AUTOPHAGY, 2019, 页码: 15 作者:  Zhang, Sulin;  Yang, Zhiwen;  Bao, Weilian;  Liu, Lixin;  You, Yan 收藏  |  浏览/下载：72/0  |  提交时间：2020/07/01 Colorectal cancer  macroautophagy  SNX10  SRC  tumor growth   Non-viral gene delivery for cancer immunotherapy 期刊论文 JOURNAL OF GENE MEDICINE, 2019, 卷号: 21, 期号: 7, 页码: 11 作者:  Wang, Weiqi;  Saeed, Madiha;  Zhou, Yao;  Yang, Lili;  Wang, Dangge 收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 cancer immunotherapy  gene delivery  nanoparticles  stimuli-responsive  tumor microenvironment