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期刊论文 [671]
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2019 [671]
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发表日期:2019
内容类型:期刊论文
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alpha-Mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders in mice
期刊论文
AGING-US, 2019, 卷号: 11, 期号: 23, 页码: 11084-11110
作者:
Li, Dan
;
Liu, Qianyu
;
Lu, Xiuqiang
;
Li, Zhengqiu
;
Wang, Chunming
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
alpha-mangostin
aging
adiposity
adipose tissue inflammation
macrophage
RepSox, a small molecule inhibitor of the TGF beta receptor, induces brown adipogenesis and browning of white adipocytes
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 12, 页码: 1523-1531
作者:
Tu, Wan-zhi
;
Fu, Yan-bin
;
Xie, Xin
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/07/01
RepSox
brown adipogenesis
TGF-beta receptor
TGF-beta inhibitor
adipocyte
differentiation
Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia via Promoting Glucose Oxidation
期刊论文
DIABETES, 2019, 卷号: 68, 期号: 12, 页码: 2197-2209
作者:
Jiang, Haowen
;
Jin, Jia
;
Duan, Yanan
;
Xie, Zhifu
;
Li, Yufeng
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Inhibition of PTP1B blocks pancreatic cancer progression by targeting the PKM2/AMPK/mTOC1 pathway
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 15
作者:
Xu, Qi
;
Wu, Ning
;
Li, Xiangqian
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/03/20
The mediated role of complement C3 in PM2.5 exposure and type 2 diabetes mellitus: an elderly panel study in Beijing, China
期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2019, 卷号: 26, 期号: 33, 页码: 34479-34486
作者:
Tong, Yuanren
;
Pei, Lu
;
Luo, Kai
;
Zhao, Meiduo
;
Xu, Jing
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  |  
浏览/下载:7/0
  |  
提交时间:2020/05/19
Diabetes mellitus
T2DMpopulation
PM2.5
C3
Mediation effects
A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1604, 页码: 13
作者:
Yisimayili, Zainaipuguli
;
Abdulla, Rahima
;
Tian, Qiang
;
Wang, Yangyang
;
Chen, Mingcang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/07/01
Punica granatum L. flowers
Polyphenols
Ellagitannin
Metabolism
HPLC-Q-TOF-MS2
Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 43, 页码: 21732-21738
作者:
Liu, Bin
;
Zhang, Zhijian
;
Hu, Yanyun
;
Lu, Yan
;
Li, Duanzhuo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2020/07/01
type 2 diabetes
gluconeogenesis
hepatic glucose production
ER stress
USP14
Design, synthesis and biological evaluation of 6-deoxy O-spiroketal C-arylglucosides as novel renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 398-416
作者:
Wang, Yibing
;
Lou, Yang
;
Wang, Jiang
;
Li, Dan
;
Chen, Hui
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
SGLT2 inhibitors
Diabetes
Sugar modification
Structure-activity relationship
Urinary glucose excretion
Oral glucose tolerance
Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16
作者:
He, Yulong
;
Dou, Huixia
;
Gao, Dingding
;
Wang, Ting
;
Zhang, Mingming
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Dual FABP4/5 inhibitor
Structure-based design
Lipolysis inhibition
Anti-inflammatory effects
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
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