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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Characteristics of hERG and hNav1.5 channel blockade by sulcardine sulfate, a novel anti-arrhythmic compound 期刊论文 European journal of pharmacology, 2018, 卷号: 844, 页码: 130-138 作者:  Chen, Weihai;  Gan, Lu;  Wang, Yiping 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 Discovery of Potent Benzocycloalkane Derived Diapophytoene Desaturase Inhibitors with an Enhanced Safety Profile for the Treatment of MRSA, VISA, and LRSA Infections 期刊论文 ACS INFECTIOUS DISEASES, 2018, 卷号: 4, 期号: 3, 页码: 208-217 作者:  Li, Baoli;  Ni, Shuaishuai;  Chen, Feifei;  Mao, Fei;  Wei, Hanwen 收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 Staphylococcus aureus  diapophytoene desaturase  methicillin-resistant Staphylococcus aureus  hERG safety   Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant Staphylococcus aureus 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 3, 页码: 233-237 作者:  Ni, Shuaishuai;  Li, Baoli;  Chen, Feifei;  Wei, Hanwen;  Mao, Fei 收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Virulence factor  pigment  multidrug resistant MRSA  CrtN inhibitor   Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 235-251 作者:  Wei, Hanwen;  Mao, Fei;  Ni, Shuaishuai;  Chen, Feifei;  Li, Baoli 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 CrtN inhibitor  STX biosynthesis  Pigment inhibitory activity  Resistant S. aureus   Synthesis and biological evaluation of a series of multi-target N-substituted cyclic imide derivatives with potential antipsychotic effect 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 74-85 作者:  Xu, Mingshuo;  Wang, Yu;  Yang, Feipu;  Wu, Chunhui;  Wang, Zhen 收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 Antipsychotic  Cyclic imide  Multi-target  5-HT1A receptor   Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 1, 页码: 224-250 作者:  Li, Baoli;  Ni, Shuaishuai;  Mao, Fei;  Chen, Feifei;  Liu, Yifu 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 F463L increases the potential of dofetilide on human ether-a-go-go-related gene (hERG) channels 期刊论文 MICROSCOPY RESEARCH AND TECHNIQUE, 2018, 卷号: 81, 页码: 663-668 作者:  Cheng, Gong;  Wu, Jine;  Han, Wenqi;  Sun, Chaofeng 收藏  |  浏览/下载：3/0  |  提交时间：2019/11/19 drug-induced LQTS  Dofetilide  whole-cell patch  mutation  hERG gene   An in Vitro Assay of hERG K+ Channel Potency for a New EGFR Inhibitor FHND004 期刊论文 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Jin, Tao;  Hu, Bingxue;  Chen, Shanshan;  Wang, Qiang;  Dong, Xue 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/05 FHND004  EGFR inhibitor  human ether-a-go-go-related gene  inhibitory effect  cardiac safety   A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport. 期刊论文 Journal of cardiology, 2018 作者:  Wu Jie;  Sakaguchi Tomoko;  Takenaka Kotoe;  Toyoda Futoshi;  Tsuji Keiko 收藏  |  浏览/下载：5/0  |  提交时间：2019/11/26 Fluorescence resonance energy transfer  Patch-clamp  hERG  Long QT syndrome  KCNQ1-T587M   A hERG mutation E1039X produced a synergistic lesion on &ITI&ITKs together with KCNQ1-R174C mutation in a LQTS family with three compound mutations 期刊论文 SCIENTIFIC REPORTS, 2018, 卷号: 8 作者:  Wu, Jie;  Mizusawa, Yuka;  Ohno, Seiko;  Ding, Wei-Guang;  Higaki, Takashi 收藏  |  浏览/下载：3/0  |  提交时间：2019/11/26