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科研机构
上海药物研究所 [4]
上海生物化学与细胞生... [4]
北京航空航天大学 [1]
武汉病毒研究所 [1]
内容类型
期刊论文 [9]
会议论文 [1]
发表日期
2018 [10]
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Structural characterization and analysis of human immunodeficiency virus encapsulating quantum dots
期刊论文
Journal of nanoscience and nanotechnology, 2018, 卷号: 18, 期号: 7, 页码: 4487-4494
作者:
Yin, Wen
;
Li, Wei
;
Li, Qin
;
Qin, Chong
;
Zhang, Zhiping
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浏览/下载:57/0
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提交时间:2019/05/08
Hiv-1
Quantum dot
Structure
Negative staining
Image
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
期刊论文
NATURE, 2018, 卷号: 558, 期号: 7711, 页码: 553-+
作者:
Kang, Yanyong
;
Kuybeda, Oleg
;
de Waal, Parker W.
;
Mukherjee, Somnath
;
Van Eps, Ned
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  |  
浏览/下载:80/0
  |  
提交时间:2019/01/08
Structural studies and drug discovery of G protein-coupled receptors
期刊论文
Kexue Tongbao/Chinese Science Bulletin, 2018, 卷号: 63, 期号: 14, 页码: 1361-1373
作者:
Yang, Zhenlin
;
Wu, Beili
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  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex
期刊论文
NATURE, 2018, 卷号: 555, 期号: 7694, 页码: 121-+
作者:
Liang, Yi-Lynn
;
Khoshouei, Maryam
;
Glukhova, Alisa
;
Furness, Sebastian G. B.
;
Zhao, Peishen
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  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Structure, Immunogenicity, and Protective Mechanism of an Engineered Enterovirus 71-Like Particle Vaccine Mimicking 80S Empty Capsid
期刊论文
JOURNAL OF VIROLOGY, 2018, 卷号: 92, 期号: 1, 页码: -
作者:
Wang, Xiaoli
;
Ku, Zhiqiang
;
Ye, Xiaohua
;
Liu, Qingwei
;
Zhang, Wei
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  |  
浏览/下载:95/0
  |  
提交时间:2019/04/28
Virus-like Particles
Antibody-dependent Enhancement
Coxsackievirus A16
Mouth-disease
Neutralizing Antibodies
Monoclonal-antibodies
Protein Vp4
Cryoelectron Microscopy
Cellular Receptor
Viral Entry
Development of a yeast internal-subunit eGFP labeling strategy and its application in subunit identification in eukaryotic group II chaperonin TRiC/CCT
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8, 期号: 1, 页码: -
作者:
Zang, Yunxiang
;
Wang, Huping
;
Cui, Zhicheng
;
Jin, Mingliang
;
Liu, Caixuan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/04/28
Resolution Cryo-em
Electron-microscopy
Saccharomyces-cerevisiae
Molecular Chaperones
Protein Complexes
Crystal-structure
Cct
Mechanism
Versatile
Proteostasis
Yeast Inner-Subunit PA-NZ-1 Labeling Strategy for Accurate Subunit Identification in a Macromolecular Complex through Cryo-EM Analysis
期刊论文
JOURNAL OF MOLECULAR BIOLOGY, 2018, 卷号: 430, 期号: 10, 页码: 1417-1425
作者:
Wang, Huping
;
Han, Wenyu
;
Cong, Yao
;
Takagi, Junichi
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  |  
浏览/下载:27/0
  |  
提交时间:2019/04/28
Particle Electron-microscopy
Eukaryotic Chaperonin
Cryoelectron Microscopy
Molecular Chaperones
Crystal-structure
Pa Tag
Protein
Cct
Resolution
Tric/cct
A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles
期刊论文
JOURNAL OF VIROLOGY, 2018, 卷号: 92, 期号: 2, 页码: e01257-17
作者:
Chen, Jinhuan
;
Zhang, Xiang
;
Cong, Yao
;
Zhang, Chao
;
Zhou, Yu
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  |  
浏览/下载:69/0
  |  
提交时间:2019/04/28
Virus-like Particles
Neutralizing Linear Epitopes
Human Enterovirus 71
Mouth-disease
Synthetic Peptides
Atomic-resolution
Capsid Protein
Atypical Hand
Salt Bridges
Cryo-em
A Method for Fully Automated Particle Picking in Cryo-Electron Microscopy Based on a CNN
会议论文
ACM-BCB 2018 - Proceedings of the 2018 ACM International Conference on Bioinformatics, Computational Biology, and Health Informatics
作者:
Da, T.
;
Ding, J.
;
Yang, L.
;
Chirikjian, G.
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  |  
浏览/下载:9/0
  |  
提交时间:2019/12/30
Bioinformatics
Electron microscopy
Image reconstruction
Medical imaging
Neural networks
Convolutional Neural Networks (CNN)
Cryo-electron microscopies (cryo- em)
Cryo-electron microscopy
Cryo-em
Data preprocessing
Histogram equalizations
Human intervention
Picking efficiency
Electron microscopes
Structural studies and drug discovery of G protein-coupled receptors
期刊论文
Chinese Science Bulletin, 2018, 卷号: 63, 期号: 14, 页码: 1362-1373
作者:
Yang Zhenlin
;
Wu Beili
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  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
G protein-coupled receptor
drug target
3D structure
ligand
structure-based drug discovery
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