×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
上海药物研究所 [3]
四川大学 [2]
湖南大学 [2]
宁波材料技术与工程研... [1]
山东大学 [1]
复旦大学上海医学院 [1]
更多...
内容类型
期刊论文 [11]
发表日期
2018 [11]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共11条,第1-10条
帮助
限定条件
发表日期:2018
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors
期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:
Wang, Xinyi
;
Ai, Jing
;
Liu, Hongyan
;
Peng, Xia
;
Chen, Hui
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
New microtubulin inhibitor MT189 suppresses angiogenesis via the JNK-VEGF/VEGFR2 signaling axis
期刊论文
CANCER LETTERS, 2018, 卷号: 416, 页码: 57-65
作者:
Xu, Lin
;
Wang, Wei
;
Meng, Tao
;
Ma, Lan-Ping
;
Tong, Lin-Jiang
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
MT189
Microtubulin inhibitor
VEGF
Src
JNK
Cell adhesion
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 817-842
作者:
Zhou, Pengfei
;
Liang, Yuru
;
Zhang, Hao
;
Jiang, Hao
;
Feng, Kechang
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144
作者:
Zhou, Pengfei
;
Liang, Yuru
;
Zhang, Hao
;
Jiang, Hao
;
Feng, Kechang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
Recent Developments on Phenstatins as Potent Antimitotic Agents.
期刊论文
Current medicinal chemistry, 2018, 卷号: 25, 期号: 20, 页码: 2329-2352
作者:
Chen, Xing
;
Wang, Shi-Meng
;
Kumar, Gajjela Bharath
;
Bare, Grant A. L.
;
Leng, Jing
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/04
Antimitotic activity
Colchicine binding site
Cytotoxic activity
Structure-activity relationship
Tubulin polymerization inhibition
phenstatins.
The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: Vol.293 No.24, 页码: 9461-9472
作者:
Yang, JH
;
Yan, W
;
Yu, YM
;
Wang, YX
;
Yang, T
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/02/25
microtubule
cancer prevention
cancer
natural product
tubulin
X-ray crystallography
drug resistance
Chalcone
Colchicine
Millepachine
s-trans conformation
Tubulin
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy
期刊论文
Journal of Medicinal Chemistry, 2018, 卷号: Vol.61 No.4, 页码: 1704-1718
作者:
Banerjee, S.
;
Arnst, K.E.
;
Wang, Y.
;
Kumar, G.
;
Deng, S.
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/02/25
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 927-933
作者:
Wu, Xingkang
;
Shen, Yuemao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
PMN
Colorectal cancer
Mitotic arrest
Microtubule
Apoptosis
p53
Synthesis, Molecular Properties Prediction and Biological Evaluation of Indole-Vinyl Sulfone Derivatives as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site
期刊论文
Bioorganic Chemistry, 2018
作者:
Wenlong Li
;
Honghao Sun
;
Feijie Xu
;
Wen Shuai
;
Jie Liu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
Tubulin
inhibitor
Vinyl
sulfone
Indole
Colchicine
site
Drug-likeness
Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.157, 页码: 1068-1080
作者:
Li, Wenlong
;
Yin, Ying
;
Yao, Hong
;
Shuai, Wen
;
Sun, Honghao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/26
Tubulin
inhibitors
Vinyl
sulfone
Colchicine
binding
site
Anti-tumor
activity
©版权所有 ©2017 CSpace - Powered by
CSpace