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The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors 期刊论文
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:  Wang, Xinyi;  Ai, Jing;  Liu, Hongyan;  Peng, Xia;  Chen, Hui
收藏  |  浏览/下载:135/0  |  提交时间:2019/01/08
New microtubulin inhibitor MT189 suppresses angiogenesis via the JNK-VEGF/VEGFR2 signaling axis 期刊论文
CANCER LETTERS, 2018, 卷号: 416, 页码: 57-65
作者:  Xu, Lin;  Wang, Wei;  Meng, Tao;  Ma, Lan-Ping;  Tong, Lin-Jiang
收藏  |  浏览/下载:21/0  |  提交时间:2019/01/08
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 817-842
作者:  Zhou, Pengfei;  Liang, Yuru;  Zhang, Hao;  Jiang, Hao;  Feng, Kechang
收藏  |  浏览/下载:16/0  |  提交时间:2019/01/08
Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral beta-lactam bridged combretastatin A-4 analogues as potent antitumor agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144
作者:  Zhou, Pengfei;  Liang, Yuru;  Zhang, Hao;  Jiang, Hao;  Feng, Kechang
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/05
Recent Developments on Phenstatins as Potent Antimitotic Agents. 期刊论文
Current medicinal chemistry, 2018, 卷号: 25, 期号: 20, 页码: 2329-2352
作者:  Chen, Xing;  Wang, Shi-Meng;  Kumar, Gajjela Bharath;  Bare, Grant A. L.;  Leng, Jing
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/04
The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: Vol.293 No.24, 页码: 9461-9472
作者:  Yang, JH;  Yan, W;  Yu, YM;  Wang, YX;  Yang, T
收藏  |  浏览/下载:4/0  |  提交时间:2019/02/25
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy 期刊论文
Journal of Medicinal Chemistry, 2018, 卷号: Vol.61 No.4, 页码: 1704-1718
作者:  Banerjee, S.;  Arnst, K.E.;  Wang, Y.;  Kumar, G.;  Deng, S.
收藏  |  浏览/下载:4/0  |  提交时间:2019/02/25
PMN inhibits colorectal cancer cells through inducing mitotic arrest and p53-dependent apoptosis via the inhibition of tubulin polymerization 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 927-933
作者:  Wu, Xingkang;  Shen, Yuemao
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
Synthesis, Molecular Properties Prediction and Biological Evaluation of Indole-Vinyl Sulfone Derivatives as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site 期刊论文
Bioorganic Chemistry, 2018
作者:  Wenlong Li;  Honghao Sun;  Feijie Xu;  Wen Shuai;  Jie Liu
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/26
Discovery of novel vinyl sulfone derivatives as anti-tumor agents with microtubule polymerization inhibitory and vascular disrupting activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.157, 页码: 1068-1080
作者:  Li, Wenlong;  Yin, Ying;  Yao, Hong;  Shuai, Wen;  Sun, Honghao
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/26


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