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浏览/检索结果: 共10条，第1-10条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414 作者:  Wang, Yibing;  Liu, Hong 收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08 Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文 CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463 作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu 收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08 cannabinoids  CB1R  CB2R  heteroaryl pyrimidines  heteroaryl triazines  ligands   7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263 作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun 收藏  |  浏览/下载：80/0  |  提交时间：2019/01/08 7 beta-Methyl-nepenthone analogues  KOR ligands  Concept of hybridization  Opioid receptor binding and functional activities   Molecular Dynamics Simulations Revealed the Regulation of Ligands to the Interactions between Androgen Receptor and Its Coactivator 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2018, 卷号: 58, 期号: 8, 页码: 1652-1661 作者:  Liu, Na;  Zhou, Wenfang;  Guo, Yue;  Wang, Junmei;  Fu, Weitao 收藏  |  浏览/下载：62/0  |  提交时间：2018/11/05 Single-molecule force spectroscopy study of interactions between angiotensin II type 1 receptor and different biased ligands in living cells 期刊论文 ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 卷号: 410, 期号: 14, 页码: 3275-3284 作者:  Li, Wenhui;  Xu, Jiachao;  Kou, Xiaolong;  Zhao, Rong;  Zhou, Wei 收藏  |  浏览/下载：32/0  |  提交时间：2019/04/09 Angiotensin Ii Type 1 Receptor  Biased Ligands  Atomic Force Microscopy  Single-molecule Force Spectroscopy  Energy Landscape   Structural basis of ligand binding modes at the neuropeptide Y Y-1 receptor 期刊论文 NATURE, 2018, 卷号: 556, 期号: 7702, 页码: 520-+ 作者:  Yang, Zhenlin;  Han, Shuo;  Keller, Max;  Kaiser, Anette;  Bender, Brian J. 收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacy 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 212-242 作者:  Dal Maso, Emma;  Zhu, Yue;  Vi Pham;  Reynolds, Christopher A.;  Deganutti, Giuseppe 收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 G protein-coupled receptor  Calcitonin receptor  GPCR structure-function  Biased agonism  Molecular modelling   Structure of the glucagon receptor in complex with a glucagon analogue 期刊论文 NATURE, 2018, 卷号: 553, 期号: 7686, 页码: 106-+ 作者:  Zhang, Haonan;  Qiao, Anna;  Yang, Linlin;  Van Eps, Ned;  Frederiksen, Klaus S. 收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 Structural determinants of 5-HT2B receptor activation and biased agonism 期刊论文 NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018, 卷号: 25, 期号: 9, 页码: 787-+ 作者:  McCorvy, John D.;  Wacker, Daniel;  Wang, Sheng;  Agegnehu, Bemnat;  Lansu, Katherine 收藏  |  浏览/下载：40/0  |  提交时间：2019/04/28 Protein-coupled Receptors  Valvular Heart-disease  Stabilized Active State  Crystal-structure  Serotonin Receptors  Nanobody  Drug  Fenfluramine  Pharmacology  Ligands   discoveryofnovelandrogenreceptorligandsbystructurebasedvirtualscreeningandbioassays 期刊论文 genomicsproteomicsbioinformatics, 2018, 卷号: 16, 期号: 6, 页码: 416 作者:  Zhou Wenfang;  Duan Mojie;  Fu Weitao;  Pang Jinping;  Tang Qin 收藏  |  浏览/下载：25/0  |  提交时间：2020/01/14