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上海药物研究所 [14]
新疆理化技术研究所 [3]
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期刊论文 [54]
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2018 [54]
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Enhanced interaction between SEC2 mutant and TCR V induces MHC II-independent activation of T cells via PKC/NF-B and IL-2R/STAT5 signaling pathways
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 51, 页码: 19771-19784
作者:
Fu, Xuanhe
;
Xu, Mingkai
;
Song, Yubo
;
Li, Yongqiang
;
Zhang, Huiwen
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/06/04
interleukin
NF-B (NF-KB)
STAT transcription factor
signaling
signal transduction
IL-2
staphylococcal enterotoxin C2
superantigen
T-cell receptor
T-cell activation
Oocyte-specific maternal Slbp2 is required for replication-dependent histone storage and early nuclear cleavage in zebrafish oogenesis and embryogenesis
期刊论文
RNA, 2018, 卷号: 24, 期号: 12, 页码: 1738-1748
作者:
He, Wen-Xia
;
Wu, Min
;
Liu, Zhen
;
Li, Zhi
;
Wang, Yang
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  |  
浏览/下载:70/0
  |  
提交时间:2019/07/02
slbp2
replication-dependent histones
ribosomal proteins
maternal effect
oogenesis
early embryogenesis
Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection
期刊论文
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2018, 卷号: 138, 期号: 4, 页码: 247-256
作者:
Yao, Xingang
;
Guo, Songxin
;
Wu, Wenyu
;
Wang, Jinan
;
Wu, Shengen
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
RdRp inhibitor
Quinazolinone derivative
DENV2 infection
VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC
期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2018, 卷号: 129, 页码: 177-185
作者:
Zhou, Ling
;
Yi, Yuetao
;
Yuan, Qing
;
Zhang, Jing
;
Li, Youjie
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  |  
浏览/下载:19/0
  |  
提交时间:2020/07/08
Vanadyl alginate oligosaccharides
Non-small cell lung cancer
ROS
AKT
PTEN
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells
期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Jiang, Bo
;
Shi, Dayong
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/05/15
antiangiogenesis
curcumin analogs
hypoxia-inducible factor-1 alpha
human umbilical vein endothelial cells
vascular endothelial growth factor
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells
期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Jiang, Bo
;
Shi, Dayong
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2018/12/21
antiangiogenesis
curcumin analogs
hypoxia-inducible factor-1 alpha
human umbilical vein endothelial cells
vascular endothelial growth factor
BF211, a derivative of bufalin, enhances the cytocidal effects in multiple myeloma cells by inhibiting the IL-6/JAK2/STAT3 pathway
期刊论文
International immunopharmacology, 2018, 卷号: 64, 页码: 24-32
作者:
Wu, Xiao-Yu
;
Tian, Fang
;
Su, Min-Hui
;
Wu, Min
;
Huang, Yue
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  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:
Wang, Beilei
;
Wu, Jiaxin
;
Wu, Yun
;
Chen, Cheng
;
Zou, Fengming
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/12/25
CDK9
Kinase inhibitor
Structure-activity relationship
Leukemia
Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways
期刊论文
RADIOTHERAPY AND ONCOLOGY, 2018, 卷号: 129, 期号: 1, 页码: 84-94
作者:
Liu, Xiongxiong
;
Li, Ping
;
Hirayama, Ryoichi
;
Niu, Yuzhen
;
Liu, Xinguo
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/10/09
Genistein
DNA-PKcs
Carbon ion radiotherapy
Radiosensitization
DSB repair
Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition
期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2018, 卷号: 17, 期号: 10, 页码: 2005-2017
作者:
Wang, Weixuan
;
Hu, Yadong
;
Yang, Changmei
;
Zhu, Songbiao
;
Wang, Xiaofei
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  |  
浏览/下载:35/0
  |  
提交时间:2020/12/24
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