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科研机构
复旦大学上海医学院 [19]
内容类型
期刊论文 [19]
发表日期
2018 [19]
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发表日期:2018
专题:复旦大学上海医学院
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From hit to lead: Structure-based discovery of naphthalene-1 sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 154
作者:
Gao, Ding-Ding
;
Dou, Hui-Xia
;
Su, Hai-Xia
;
Zhang, Ming-Ming
;
Wang, Ting
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
FABP4 inhibitors
FABP3 sparing
Structure-based design strategy
X-ray crystallography
Adenine derivatives invert high glucose-induced thioredoxin-interacting protein overexpression
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2018, 卷号: 92, 期号: 6
作者:
Zhong, Li
;
Liu, Qing
;
Ting, Yan Sie
;
Vun Yien Thien
;
Kalong, Nurwafa Syafiqah Binti
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/12/05
adenine derivative
structural optimization
thioredoxin-binding protein-2
thioredoxin-interacting protein
vitamin D3-upregulated protein-1
Kruppel-like factor 10 (KLF10) is transactivated by the transcription factor C/EBP and involved in early 3T3-L1 preadipocyte differentiation
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36
作者:
Liu, Yuan
;
Peng, Wan-Qiu
;
Guo, Ying-Ying
;
Liu, Yang
;
Tang, Qi-Qun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
adipogenesis
Kruppel-like factor (KLF)
CCAAT-enhancer-binding protein (C
EBP)
cell proliferation
transcription regulation
histone deacetylase 1 (HDAC1)
adipose tissue
3T3-L1 preadipocytes
adipocyte differentiation
C
EBP
Kruppel-like factor (KLF)
mitotic clonal expansion
Metformin attenuates triglyceride accumulation in HepG2 cells through decreasing stearyl-coenzyme A desaturase 1 expression
期刊论文
LIPIDS IN HEALTH AND DISEASE, 2018, 卷号: 17
作者:
Sun, Xiaoyang
;
Zhu, Xiaopeng
;
Yan, Hongmei
;
Xia, Mingfeng
;
Chang, Xinxia
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
Nonalcoholic fatty liver disease
NAFLD
Metformin
Stearyl-coenzyme A desaturase 1
SCD1
Adenosine monophosphate-activated protein kinase
AMPK
Sterol regulatory element-binding protein-1c
SREBP-1c
Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial-mesenchymal transition
期刊论文
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2018, 卷号: 10, 期号: 11
作者:
Zhang, Xin-Yu
;
Gao, Ping-Ting
;
Yang, Xuan
;
Cai, Jia-Bin
;
Ding, Guang-Yu
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Selenium-binding protein 1
intrahepatic cholangiocarcinoma
prognosis
epithelial-mesenchymal transition
Far Upstream Element-Binding Protein 1 Regulates LSD1 Alternative Splicing to Promote Terminal Differentiation of Neural Progenitors
期刊论文
STEM CELL REPORTS, 2018, 卷号: 10, 期号: 4
作者:
Na, Yoonmi
;
Kim, Do-Yeon
;
Zhang, Tuo
;
Yao, Jun
;
Oh, Hwanhee
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24
作者:
Zuo, Xiaoli
;
Rong, Bowen
;
Li, Li
;
Lv, Ruitu
;
Lan, Fei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
spermatogenesis
histone modification
histone methylation
testis
reproduction
acrosome biogenesis
histone-to-protamine transition
Setd2
spermiogenesis
HBP induces the expression of monocyte chemoattractant protein-1 via the FAK/PI3K/AKT and p38 MAPK/NF-kappa B pathways in vascular endothelial cells
期刊论文
CELLULAR SIGNALLING, 2018, 卷号: 43
作者:
Chang, Mengling
;
Guo, Feng
;
Zhou, Zengding
;
Huang, Xiaoqin
;
Yi, Lei
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/05
Heparin binding protein (HBP)
Monocyte chemotactic protein 1(MCP-1)
Vascular endothelial cells
Inflammation
Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 18, 期号: 5
作者:
Li, Dandan
;
Ren, Weiying
;
Jiang, Zhilong
;
Zhu, Lei
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
acute lung injury and acute respiratory distress syndrome
alveolar macrophages
p38 mitogen-activated protein kinase signaling pathway
pyroptosis
nucleotide-binding domain
leucine-rich-containing family
pyrin domain-containing-3 inflammasome
Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer
期刊论文
WORLD JOURNAL OF GASTROENTEROLOGY, 2018, 卷号: 24, 期号: 43
作者:
Xu, Wen-Yan
;
Hu, Qiang-Sheng
;
Qin, Yi
;
Zhang, Bo
;
Liu, Wen-Sheng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Pancreatic cancer
Zinc finger E-box binding homeobox-1
Sirtuin 3
Methyl-CpG binding domain protein 1
Glycolysis
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