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PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266
作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527
作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang
收藏  |  浏览/下载:55/0  |  提交时间:2019/01/08
Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531
作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang
收藏  |  浏览/下载:30/0  |  提交时间:2019/01/08
Targeted delivery of sirna using rgdfc-conjugated functionalized selenium nanoparticles for anticancer therapy 期刊论文
Journal of materials chemistry b, 2017, 卷号: 5, 期号: 33, 页码: 6941-6952
作者:  Xia, Yu;  Lin, Zhengfang;  Li, Yinghua;  Zhao, Mingqi;  Wang, Changbing
收藏  |  浏览/下载:32/0  |  提交时间:2019/05/08
Cyanobacterial peptides as a prototype for the design of cathepsin D inhibitors 期刊论文
JOURNAL OF PEPTIDE SCIENCE, 2017, 卷号: 23, 期号: 9, 页码: 701-706
作者:  Xu, Hao;  Bao, Keting;  Tang, Shuai;  Ai, Jing;  Hu, Haiyan
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08
Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 35, 页码: 59086-59102
作者:  Zhang, Xuesai;  Li, Qingrou;  Zhao, Hui;  Ma, Lanping;  Meng, Tao
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Design, Synthesis and Anti-Proliferative Activities of 2,6-Substituted Thieno[3,2-d] pyrimidine Derivatives Containing ElectrophilicWarheads 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 5
作者:  Zhang, Qiumeng;  Hu, Zonglong;  Shen, Qianqian;  Chen, Yi;  Lu, Wei
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Synthesis and cytotoxic activity of novel tetrahydrobenzodifuran-imidazolium salt derivatives 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 8, 页码: 1808-1814
作者:  Zhang, Chao-Bo;  Liu, Yang;  Liu, Zheng-Fen;  Duan, Sheng-Zu;  Li, Min-Yan
收藏  |  浏览/下载:25/0  |  提交时间:2017/06/30
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:  Wang, Aoli;  Li, Xixiang;  Wu, Hong;  Zou, Fengming;  Yan, Xiao-E
收藏  |  浏览/下载:34/0  |  提交时间:2018/07/26
Discovery of (R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one (CHMFL-EGFR-202) as a Novel Irreversible EGFR Mutant Kinase Inhibitor with a Distinct Binding Mode 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 7, 页码: 2944-2962
作者:  Wang, Aoli;  Li, Xixiang;  Wu, Hong;  Zou, Fengming;  Yan, Xiao-E
收藏  |  浏览/下载:41/0  |  提交时间:2018/07/26


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