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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2017     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527 作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang 收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08 Epidermal growth factor receptor  Tyrosine kinase inhibitors  Non-small cell lung cancer  T790M  Mutant-selective   Structure-Guided Design of C4-alkyl-1,4-dihydro-2H-pyrimido[4,5-d][1,3]oxazin-2-ones as Potent and Mutant-Selective Epidermal Growth Factor Receptor (EGFR) L858R/T790M Inhibitors 期刊论文 SCIENTIFIC REPORTS, 2017, 卷号: 7 作者:  Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Sun, Deheng;  Zhao, Zhenjiang 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Mimicking the BIM BH3 domain overcomes resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 65 作者:  Xia, Jinjing;  Bai, Hao;  Yan, Bo;  Li, Rong;  Shao, Minhua 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/05 epidermal growth factor receptor (EGFR)  tyrosine kinase inhibitors (TKIs)  BIM deletion polymorphism  erlotinib  ABT-737   Polyphyllin I Overcomes EMT-Associated Resistance to Erlotinib in Lung Cancer Cells via IL-6/STAT3 Pathway Inhibition 期刊论文 BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2017, 卷号: 40, 期号: 8 作者:  Lou, Wei;  Chen, Yan;  Zhu, Ke-ying;  Deng, Huizi;  Wu, Tianhao 收藏  |  浏览/下载：10/0  |  提交时间：2019/12/05 lung cancer  acquired resistance  erlotinib  polyphyllin I  epithelial-mesenchymal transition  interleukin-6   Co-delivery of oxygen and erlotinib by aptamer-modified liposomal complexes to reverse hypoxia-induced drug resistance in lung cancer 期刊论文 BIOMATERIALS, 2017, 卷号: 145, 页码: 56-71 作者:  Li, Fengqiao;  Mei, Hao;  Gao, Yu;  Xie, Xiaodong;  Nie, Huifang 收藏  |  浏览/下载：2/0  |  提交时间：2019/11/21 Liposomal complexes  NSCLC  Hypoxia  Drug resistance  PFOB   Inhibition of Histone Deacetylases Sensitizes EGFR-TKI-Resistant Non-Small Cell Lung Cancer Cells to Erlotinib In Vitro and In Vivo. 期刊论文 Br J Pharmacol, 2017 作者:  Yu W;  Lu W;  Chen G;  Cheng F;  Su H 收藏  |  浏览/下载：4/0  |  提交时间：2019/03/01 EGFR-TKI  resistance  Non-small  cell  lung  cancer  epidermal  growth  factor  receptor  erlotinib  histone  deacetylase