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浏览/检索结果: 共52条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61 作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun 收藏  |  浏览/下载：136/0  |  提交时间：2019/01/08 Pyrotinib  HER2-postive breast cancer  Irreversible EGFR/HER2 dual tyrosine kinase  inhibitor  Preclinical  Clinical  Safety  Drug metabolism   Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990 作者:  Xie, Chengying;  Chen, Xiangling;  Zheng, Mingyue;  Liu, Xiaohong;  Wang, Hongbin 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 BEZ235  drug resistance  mTOR  PI3K  SHR8443   Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1655-1662 作者:  Dong, Xin-yue;  Lang, Tian-qun;  Yin, Qi;  Zhang, Peng-cheng;  Li, Ya-ping 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 pH-sensitive polymer  co-delivery  micelle  docetaxel  silibinin  breast cancer  mouse breast cancer cell line 4T1  metastasis   Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270 作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing;  Xie, Yi-qian 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 epigenetics  molecular docking  PRMT1  scaffold hopping  small-molecule inhibitor   Chemical antagonism between photodynamic agents and chemotherapeutics: mechanism and avoidance 期刊论文 CHEMICAL COMMUNICATIONS, 2017, 卷号: 53, 期号: 92, 页码: 12438-12441 作者:  Meng, Qingshuo;  Meng, Jia;  Ran, Wei;  Su, Jinghan;  Yang, Yuguang 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues 期刊论文 ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 卷号: 15, 期号: 44, 页码: 9352-9361 作者:  Jiang, Hao;  Xing, Jing;  Wang, Chen;  Zhang, Hao;  Yue, Liyan 收藏  |  浏览/下载：108/0  |  提交时间：2019/01/08 Remote Loading of Small-Molecule Therapeutics into Cholesterol-Enriched Cell-Membrane-Derived Vesicles 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 卷号: 56, 期号: 45, 页码: 14075-14079 作者:  Zhang, Xinxin;  Angsantikul, Pavimol;  Ying, Man;  Zhuang, Jia;  Zhang, Qiangzhe 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 biocompatibility  biomimetic nanotechnology  cell membrane  drug delivery  remote loading   Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review 期刊论文 MARINE DRUGS, 2017, 卷号: 15, 期号: 11 作者:  Shah, Sayed Asmat Ali;  Akhter, Najeeb;  Auckloo, Bibi Nazia;  Khan, Ishrat;  Lu, Yanbin 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 cyanobacteria  secondary metabolites  biological properties and applications   Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532 作者:  Chen, Wen-hua;  Song, Shan-shan;  Qi, Ming-hui;  Huan, Xia-juan;  Wang, Ying-qing 收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 PARP-1 inhibitor  olaparib  breast cancer  BRCA-deficient tumors   Label-free brainwide visualization of senile plaque using cryo-micro-optical sectioning tomography 期刊论文 OPTICS LETTERS, 2017, 卷号: 42, 期号: 21, 页码: 4247-4250 作者:  Luo, Yilin;  Wang, Anle;  Liu, Mengmeng;  Lei, Tian;  Zhang, Xiaochuan 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08