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浏览/检索结果: 共54条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Pharmacologic characterization of SHR8443, a novel dual inhibitor of phosphatidylinositol 3-kinase and mammalian target of rapamycin 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 64, 页码: 107977-107990 作者:  Xie, Chengying;  Chen, Xiangling;  Zheng, Mingyue;  Liu, Xiaohong;  Wang, Hongbin 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 BEZ235  drug resistance  mTOR  PI3K  SHR8443   Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat 期刊论文 NANO LETTERS, 2017, 卷号: 17, 期号: 12, 页码: 7684-7690 作者:  Peng, Huige;  Chen, Binfan;  Huang, Wei;  Tang, Yubo;  Jiang, Yifan 收藏  |  浏览/下载：65/0  |  提交时间：2019/01/08 Tumor-associated macrophages  gefitinib  vorinostat  EGFR(T790M)  nonsmall cell lung cancer  drug resistance   PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KII alpha, Inhibits the Growth of Breast Cancer Cells 期刊论文 CANCER RESEARCH, 2017, 卷号: 77, 期号: 22, 页码: 6253-6266 作者:  Li, Jiangmei;  Gao, Zhen;  Zhao, Dan;  Zhang, Lunfeng;  Qiao, Xinhua 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542 作者:  Xie, Qin;  Chen, Hui;  Ai, Jing;  Gao, Ying-lei;  Geng, Mei-yu 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 thyroid cancer  AL3810  multi-tyrosine kinases inhibitor  angiogenesis  RET   Synthesis and antitumor activity of a series of lactone-opened camptothecin derivatives 期刊论文 Journal of Asian natural products research, 2017, 页码: 1-11 作者:  Zheng, Chao;  Li, Ming-Zong;  You, Tian-Pa;  Tang, Wei-Ping;  Lou, Li-Guang 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway 期刊论文 CELL DEATH & DISEASE, 2017, 卷号: 8 作者:  Sun, Xi;  Li, Bo;  Xie, Bingqian;  Xu, Zhijian;  Chang, Gaomei 收藏  |  浏览/下载：62/0  |  提交时间：2019/01/08 Anti-proliferation activity of terpenoids isolated from Euphorbia kansui in human cancer cells and their structure-activity relationship 期刊论文 CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 10, 页码: 766-774 作者:  Hou Jin-Jun;  Shen Yao;  Yang Zhou;  Fang Lin;  Cai Lu-Ying 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Terpenoids  Anti-proliferation activity  Human cancer cells  Structure-activity relationship   Structure analysis of a novel heteroxylan from the stem of Dendrobium officinale and anti-angiogenesis activities of its sulfated derivative 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2017, 卷号: 103, 页码: 533-542 作者:  Yue, Han;  Liu, Yanqiu;  Qu, Huanhuan;  Ding, Kan 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Dendrobium officinale  Polysaccharide  Anti-angiogenesis  Heteroxylan  Sulfated derivative   Discovery, mechanism and metabolism studies of 2,3-difluorophenyl-linker-containing PARP1 inhibitors with enhanced in vivo efficacy for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 514-531 作者:  Chen, Wenhua;  Guo, Ne;  Qi, Minghui;  Dai, Haiying;  Hong, Minghuang 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Antitumor drug  BRCA1/2  PARP inhibitors  Molecular docking   LLDT-288, a novel triptolide analogue exhibits potent antitumor activity in vitro and in vivo 期刊论文 BIOMEDICINE & PHARMACOTHERAPY, 2017, 卷号: 93, 页码: 1004-1009 作者:  Xu, Hongtao;  Fan, Xiaoting;  Zhang, Guanjun;  Liu, Xiaoyu;  Li, Zhihong 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Triptolide  Natural products  Drug-resistance  CYP