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浏览/检索结果: 共112条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer 期刊论文 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61 作者:  Li, Xin;  Yang, Changyong;  Wan, Hong;  Zhang, Ge;  Feng, Jun 收藏  |  浏览/下载：136/0  |  提交时间：2019/01/08 Pyrotinib  HER2-postive breast cancer  Irreversible EGFR/HER2 dual tyrosine kinase  inhibitor  Preclinical  Clinical  Safety  Drug metabolism   Discovery of a Potential Plasma Protein Biomarker Panel for Acute-on-Chronic Liver Failure Induced by Hepatitis B Virus 期刊论文 FRONTIERS IN PHYSIOLOGY, 2017, 卷号: 8 作者:  Zhou, Ni;  Wang, Kuifeng;  Fang, Shanhua;  Zhao, Xiaoyu;  Huang, Tingting 收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 HBV-ACLF  CHB  iTRAQ  proteomics  biomarker   Bile acid signaling and bariatric surgery 期刊论文 Liver research, 2017, 卷号: 1, 期号: 4, 页码: 208-213 作者:  Tian, Jingyan;  Huang, Silvia;  Sun, Siming;  Ding, Lili;  Zhang, Eryun 收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Extending the Structural View of Class B GPCRs 期刊论文 TRENDS IN BIOCHEMICAL SCIENCES, 2017, 卷号: 42, 期号: 12, 页码: 946-960 作者:  de Graaf, Chris;  Song, Gaojie;  Cao, Can;  Zhao, Qiang;  Wang, Ming-Wei 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Assembly and architecture of the Wnt/beta-catenin signalosome at the membrane 期刊论文 BRITISH JOURNAL OF PHARMACOLOGY, 2017, 卷号: 174, 期号: 24, 页码: 4564-4574 作者:  DeBruine, Zachary J.;  Xu, H. E.;  Melcher, Karsten 收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 Calcium Promotes Human Gastric Cancer via a Novel Coupling of Calcium-Sensing Receptor and TRPV4 Channel 期刊论文 CANCER RESEARCH, 2017, 卷号: 77, 期号: 23, 页码: 6499-6512 作者:  Xie, Rui;  Xu, Jingyu;  Xiao, Yufeng;  Wu, Jilin;  Wan, Hanxing 收藏  |  浏览/下载：81/0  |  提交时间：2019/01/08 Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248 作者:  Chen, Jianzhong;  Wang, Jinan;  Zhu, Weiliang 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Baicalein ameliorates TNBS-induced colitis by suppressing TLR4/MyD88 signaling cascade and NLRP3 inflammasome activation in mice 期刊论文 Scientific reports, 2017, 卷号: 7, 期号: 1, 页码: 16374 作者:  Luo, Xiaoping;  Yu, Zhilun;  Deng, Chao;  Zhang, Jingjing;  Ren, Gaiyan 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice 期刊论文 FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8 作者:  Yu, Cunzhi;  Li, Yu;  Liu, Mingxia;  Gao, Man;  Li, Chenggang 收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 (5R)-5-hydroxytriptolide  functional knockout  cytochrome P450  testes  gamma-H2AX  RNA polymerase II  androgen receptor   Dihydroartemisinin selectively inhibits PDGFR alpha-positive ovarian cancer growth and metastasis through inducing degradation of PDGFR alpha protein 期刊论文 CELL DISCOVERY, 2017, 卷号: 3 作者:  Li, Xiaoguang;  Ba, Qian;  Liu, Yanling;  Yue, Qingxi;  Chen, Peizhan 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 Dihydroartemisinin  Epithelial-mesenchymal transition  metastasis  ovarian cancer  PDGFR alpha