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浏览/检索结果: 共53条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3 beta inhibitors and neuroprotective agents 期刊论文 PHARMAZIE, 2017, 卷号: 72, 期号: 12, 页码: 707-713 作者:  Hu, Yuanyuan 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Design, synthesis and biological evaluation of novel alpha-hederagenin derivatives with anticancer activity 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 141, 页码: 427-439 作者:  Liu, Xian-xuan;  Yang, Yan-ting;  Wang, Xiao;  Wang, Kai-yi;  Liu, Jia-qi 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 alpha-Hederagenin derivatives  Synthesis  Apoptosis  Cancer   Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1655-1662 作者:  Dong, Xin-yue;  Lang, Tian-qun;  Yin, Qi;  Zhang, Peng-cheng;  Li, Ya-ping 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 pH-sensitive polymer  co-delivery  micelle  docetaxel  silibinin  breast cancer  mouse breast cancer cell line 4T1  metastasis   6-Methoxyethylamino-numonafide inhibits hepatocellular carcinoma xenograft growth as a single agent and in combination with sorafenib 期刊论文 FASEB JOURNAL, 2017, 卷号: 31, 期号: 12, 页码: 5453-5465 作者:  Liu, Yanning;  Lou, Guohua;  Norton, John T.;  Wang, Chen;  Kandela, Irawati 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 MEAN  HCC therapeutic  combination treatment  C-MYC inhibition   Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157 作者:  Wang, Wen-Long;  Chen, Xiao-Yu;  Gao, Ya;  Gao, Li-Xin;  Sheng, Li 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Benzo[c][1,2,5] thiadiazole derivatives  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   Chemical antagonism between photodynamic agents and chemotherapeutics: mechanism and avoidance 期刊论文 CHEMICAL COMMUNICATIONS, 2017, 卷号: 53, 期号: 92, 页码: 12438-12441 作者:  Meng, Qingshuo;  Meng, Jia;  Ran, Wei;  Su, Jinghan;  Yang, Yuguang 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore 期刊论文 ONCOTARGET, 2017, 卷号: 8, 期号: 61, 页码: 104057-104071 作者:  Kuang, Shan;  Liu, Ge;  Cao, Ruobing;  Zhang, Linlin;  Yu, Qiang 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 mansouramycin C  marine-derived isoquinolinequinone  reactive oxygen species  mitochondrial permeability transition pore  anticancer drug   The miR-491-3p/Sp3/ABCB1 axis attenuates multidrug resistance of hepatocellular carcinoma 期刊论文 CANCER LETTERS, 2017, 卷号: 408, 页码: 102-111 作者:  Zhao, Yang;  Qi, Xinming;  Chen, Jing;  Wei, Wenxin;  Yu, Cunzhi 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Hepatocellular carcinoma  ABCB1  Sp3  miR-491-3p  Multidrug resistance   Nuclear Accumulation of Histone Deacetylase 4 (HDAC4) Exerts Neurotoxicity in Models of Parkinson's Disease 期刊论文 MOLECULAR NEUROBIOLOGY, 2017, 卷号: 54, 期号: 9, 页码: 6970-6983 作者:  Wu, Qimei;  Yang, Xiaoyu;  Zhang, Lei;  Zhang, Yu;  Feng, Linyin 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 HDAC4  alpha-Synuclein  Neuroprotection  Parkinson's disease  PKC   Design and synthesis of pregnenolone/2-cyanoacryloyl conjugates with dual NF-kappa B inhibitory and anti-proliferative activities 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 20, 页码: 4682-4686 作者:  Song, Jia-Li;  Zhang, Juan;  Liu, Chang-Liang;  Liu, Chao;  Zhu, Kong-Kai 收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Pregnenolone  NF-kappa B  2-Cyanoacryloyl  Michael acceptor  Anti-proliferative activity