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科研机构
上海药物研究所 [29]
内容类型
期刊论文 [28]
会议论文 [1]
发表日期
2016 [29]
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浏览/检索结果:
共29条,第1-10条
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发表日期:2016
专题:上海药物研究所
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Comparative pharmacokinetic analysis of extracts of crude and wine-processed Dipsacus asper in rats by a sensitive ultra performance liquid chromatography-tandem mass spectrometry approach
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1036, 页码: 33-41
作者:
Tao, Yi
;
Ren, Yuchao
;
Li, Weidong
;
Cai, Baochang
;
Di, Liuqing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Dipsacus asper
Wine-processed
UPLC-MS/MS
Pharmacokinetics
Pharmacokinetics and Disposition of Circulating Iridoids and Organic Acids in Rats Intravenously Receiving ReDuNing Injection
期刊论文
DRUG METABOLISM AND DISPOSITION, 2016, 卷号: 44, 期号: 11, 页码: 1853-1858
作者:
Cheng, Chen
;
Du, Feifei
;
Yu, Ke
;
Xu, Fang
;
Wang, Fengqing
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:
Guo, Diliang
;
Li, Jing
;
Lin, Henry
;
Zhou, Yu
;
Chen, Ying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127
作者:
Zhu, Yunting
;
Li, Liang
;
Zhang, Ge
;
Wan, Hong
;
Yang, Changyong
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Pyrotinib
UPLC/Q-TOF MS
Metabolism
Human
CYP3A4
Drug-drug interaction
HER2-targeted antibody drug conjugates for ovarian cancer therapy
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 卷号: 93, 页码: 274-286
作者:
Jiang, Jing
;
Dong, Lihou
;
Wang, Lei
;
Wang, Ling
;
Zhang, Jing
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
Ovarian cancer
Antibody drug conjugates (ADCs)
HER2/ErbB2
Monomethyl auristatin E (MMAE)
Safety, pharmacokinetics, and antitumor properties of anlotinib, an oral multi-target tyrosine kinase inhibitor, in patients with advanced refractory solid tumors
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2016, 卷号: 9
作者:
Sun, Yongkun
;
Niu, Wei
;
Du, Feng
;
Du, Chunxia
;
Li, Shuting
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Anlotinib
Anti-angiogenesis
Phase I study
Advanced refractory solid tumors
Pharmacokinetics
Safety
Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines
会议论文
作者:
Ren J(任进)
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines
Pharmacokinetic study of harmane and its 10 metabolites in rat after intravenous and oral administration by UPLC-ESI-MS/MS
期刊论文
Pharmaceutical biology, 2016, 卷号: 54, 期号: 9, 页码: 1768-81
作者:
Li, Shuping
;
Teng, Liang
;
Liu, Wei
;
Cheng, Xuemei
;
Jiang, Bo
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 1: Systemic evaluation of hepatic first-pass effect in vitro and in vivo
期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 533-544
作者:
Tian, Xiaoting
;
Gao, Yu
;
Xu, Zhou
;
Lian, Shan
;
Ma, Yuanjie
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
mangiferin
norathyriol
pharmacokinetics
metabolism
liver
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 2: Influence of UGT, CYP450, P-gp, and enterobacteria and the potential interaction in Rhizoma Anemarrhenae decoction with timosaponin B2 as the major contributor
期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 545-555
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Li, Zhixiong
;
Ma, Yuanjie
;
Lian, Shan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
mangiferin
norathyriol
pharmacokinetics
drug-drug interaction
timosaponin B2
Rhizoma Anemarrhenae
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