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科研机构
大连化学物理研究所 [11]
内容类型
期刊论文 [10]
会议论文 [1]
发表日期
2014 [11]
学科主题
物理化学 [3]
分析化学 [1]
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发表日期:2014
专题:大连化学物理研究所
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Insights from systems pharmacology into cardiovascular drug discovery and therapy
期刊论文
bmc systems biology, 2014, 卷号: 8
作者:
Li, Peng
;
Fu, Yingxue
;
Ru, Jinlong
;
Huang, Chao
;
Du, Jiangfeng
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2015/11/17
Cardiovascular disease
Network pharmacology
Network analysis
Drug discovery
Drug-target network
Gene-disease network
A novel systems pharmacology model for herbal medicine injection: a case using reduning injection
期刊论文
bmc complementary and alternative medicine, 2014, 卷号: 14
作者:
Yang, Haixing
;
Zhang, Wenjuan
;
Huang, Chao
;
Zhou, Wei
;
Yao, Yao
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2015/11/17
Systems pharmacology
Reduning injection
Polypharmacology
Mechanism of action
Rapid construction of a Bacterial Artificial Chromosomal (BAC) expression vector using designer DNA fragments
期刊论文
plasmid, 2014, 卷号: 76, 期号: 1, 页码: 79-86
作者:
Chen, Chao
;
Zhao, Xinqing
;
Jin, Yingyu
;
Zhao, Zongbao (Kent)
;
Suh, Joo-Won
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2015/11/16
Heterologous expression
Bacterial Artificial Chromosomal (BAC) vector
In-Fusion cloning
lambda-RED-mediated homologous recombination
Biosynthetic gene cluster
Natural product
GPCR-based drug discovery from Traditional Chinese Medicine
会议论文
2014 shanghai international conference on traditional chinese medicine and natural medicine, 中国, 2014-10-16
作者:
Zhang Y(张岩)
;
Zhang XL(张秀莉)
;
Wang CR(王超然)
;
Xue XY(薛兴亚)
;
Liang XM(梁鑫淼)
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2015/11/13
Systems pharmacology in drug discovery and therapeutic insight for herbal medicines
期刊论文
briefings in bioinformatics, 2014, 卷号: 15, 期号: 5, 页码: 710-733
作者:
Huang, Chao
;
Zheng, Chunli
;
Li, Yan
;
Wang, Yonghua
;
Lu, Aiping
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2015/11/17
systems pharmacology
herbal medicines
ADME
network pharmacology
depression
Efficient purification of active bufadienolides by a class separation method based on hydrophilic solid-phase extraction and reversed-phase high performance liquid chromatography
期刊论文
journal of pharmaceutical and biomedical analysis, 2014, 卷号: 97, 页码: 54-64
作者:
Li, Xiaolong
;
Liu, Yanfang
;
Shen, Aijin
;
Wang, Chaoran
;
Yan, Jingyu
收藏
  |  
浏览/下载:116/0
  |  
提交时间:2015/11/17
Active bufadienolides
Hydrophilic solid-phase extraction
Class separation
Purification
Toad skin
Insight into the Structural Features of Pyrazolopyrimidine- and Pyrazolopyridine-based B-Raf(V600E) Kinase Inhibitors by Computational Explorations
期刊论文
chemical biology & drug design, 2014, 卷号: 83, 期号: 6, 页码: 643-655
作者:
Li, Yan
;
Han, Chunxiao
;
Wang, Jinghui
;
Yang, Yinfeng
;
Zhang, Jingxiao
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/11/17
B-Raf(V600E) kinase
Pyrazolopyrimidine- and pyrazolopyridine-based inhibitors
3D-QSAR
docking
md
TCMSP: a database of systems pharmacology for drug discovery from herbal medicines
期刊论文
journal of cheminformatics, 2014, 卷号: 6
作者:
Ru, Jinlong
;
Li, Peng
;
Wang, Jinan
;
Zhou, Wei
;
Li, Bohui
收藏
  |  
浏览/下载:422/0
  |  
提交时间:2015/11/17
TCM
Systems pharmacology
Drug discovery
ADME
Systems pharmacology strategies for drug discovery and combination with applications to cardiovascular diseases
期刊论文
journal of ethnopharmacology, 2014, 卷号: 151, 期号: 1, 页码: 93-107
作者:
Li, Peng
;
Chen, Jianxin
;
Wang, Jinan
;
Zhou, Wei
;
Wang, Xia
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2015/11/17
Cardiovascular diseases
Drug discovery and combination
Systems pharmacology
Systems biology
Insight into the binding mode and the structural features of the pyrimidine derivatives as human A(2A) adenosine receptor antagonists
期刊论文
biosystems, 2014, 卷号: 115, 期号: 1, 页码: 13-22
作者:
Zhang, Lihui
;
Liu, Tianjun
;
Wang, Xia
;
Wang, Jinan
;
Li, Guohui
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/11/16
Pyrimidine derivatives
Human A(2A) adenosine receptor
Molecular docking
Molecular dynamics
Thermodynamic analysis
3D-QSAR
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