Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer

CORC > 水生生物研究所 > 中科院水生所知识产出（2009年前） > 水生生物分子与细胞生物学研究中心 > 期刊论文

	Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer
	Xiong, Jie 1; Wang, Guangying 1,2; Cheng, Jun 1,3; Tian, Miao 1,2; Pan, Xuming 4; Warren, Alan 5; Jiang, Chuanqi 1,2; Yuan, Dongxia 1; Miao, Wei 1
刊名	SCIENTIFIC REPORTS
	2015-10-21
卷号	5
ISSN号	2045-2322
英文摘要	Certain ciliates of the subclass Scuticociliatia (scuticociliates) are facultative parasites of fishes in which they cause a suite of diseases collectively termed scuticociliatosis. Hitherto, comparatively little was known about genetics and genomics of scuticociliates or the mechanism of scuticociliatosis. In this study, a laboratory culture of the facultatively pathogenic scuticociliate Pseudocohnilembus persalinus was established and its genome sequenced, giving the first genome of a marine ciliate. Genome-wide horizontal gene transfer (HGT) analysis showed P. persalinus has acquired many unique prokaryote-derived genes that potentially contribute to the virulence of this organism, including cell adhesion, hemolysis and heme utilization genes. These findings give new insights into our understanding of the pathology of scuticociliates.
WOS标题词	Science & Technology
类目[WOS]	Multidisciplinary Sciences
研究领域[WOS]	Science & Technology - Other Topics
关键词[WOS]	FLOUNDER PARALICHTHYS-OLIVACEUS ; TURBOT SCOPHTHALMUS-MAXIMUS ; PHOSPHOLIPASE-C ; URONEMA-MARINUM ; PHILASTERIDES-DICENTRARCHI ; RNA-SEQ ; PLASMODIUM-FALCIPARUM ; STAPHYLOCOCCUS-AUREUS ; PROTECTIVE IMMUNITY ; HEMOLYSIN-III
收录类别	SCI
语种	英语
WOS记录号	WOS:000363114000001
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/27278]
专题	水生生物研究所_水生生物分子与细胞生物学研究中心_期刊论文
作者单位	1.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Guangdong Ocean Univ, Zhanjiang 524088, Peoples R China 4.Harbin Normal Univ, Coll Life Sci & Technol, Dept Biol, Lab Protozool, Harbin 150025, Peoples R China 5.Nat Hist Museum, Dept Life Sci, London SW7 5BD, England
推荐引用方式 GB/T 7714	Xiong, Jie,Wang, Guangying,Cheng, Jun,et al. Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer[J]. SCIENTIFIC REPORTS,2015,5.
APA	Xiong, Jie.,Wang, Guangying.,Cheng, Jun.,Tian, Miao.,Pan, Xuming.,...&Miao, Wei.(2015).Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer.SCIENTIFIC REPORTS,5.
MLA	Xiong, Jie,et al."Genome of the facultative scuticociliatosis pathogen Pseudocohnilembus persalinus provides insight into its virulence through horizontal gene transfer".SCIENTIFIC REPORTS 5(2015).