Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin

	Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin
	Zhang, Min 1; He, Xiwen 1; Chen, Langxing 1; Zhang, Yukui 1,2
刊名	nanotechnology
	2011-02-11
卷号	22 期号:6
英文摘要	in this study, a novel route for the preparation of magnetite (fe(3)o(4)) nanoparticles (nps) with immobilized metal affinity ligand iminodiacetic acid (ida) charged with cu(2+) was developed. first, magnetite nanoparticles were synthesized by a hydrothermal method. charged with cu(2+), the magnetic nanoparticles (mnps) were applied to separate a model protein mixture of bovine hemoglobin (bhb) and bovine serum albumin (bsa). they could be separated completely and showed low non-specific adsorption. the morphology, structure and composition of the magnetite mnps were characterized by transmission electron microscopy, power x-ray diffraction, x-ray photoelectron spectrometry and fourier transform infrared spectroscopy. the resulting magnetite mnps charged with cu(2+) show not only a strong magnetic response to externally applied magnetic field, but are also highly specific to protein bhb. it is interesting that mnps modified with metal ligands showed a property of magnetic colloid photonic crystals. furthermore, they could efficiently remove the abundant protein bovine hemoglobin from bovine blood. they have potential application in removing abundant protein in proteomic analysis.
WOS标题词	science & technology ; technology ; physical sciences
类目[WOS]	nanoscience & nanotechnology ; materials science, multidisciplinary ; physics, applied
研究领域[WOS]	science & technology - other topics ; materials science ; physics
关键词[WOS]	iron-oxide nanoparticles ; immobilized metal-ions ; tof-ms analysis ; human serum ; biomedical applications ; facile synthesis ; microspheres ; recognition ; depletion ; nanospheres
收录类别	SCI
语种	英语
WOS记录号	WOS:000285998900020
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/142308]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Nankai Univ, Dept Chem, Tianjin 300071, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Min,He, Xiwen,Chen, Langxing,et al. Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin[J]. nanotechnology,2011,22(6).
APA	Zhang, Min,He, Xiwen,Chen, Langxing,&Zhang, Yukui.(2011).Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin.nanotechnology,22(6).
MLA	Zhang, Min,et al."Preparation and characterization of iminodiacetic acid-functionalized magnetic nanoparticles and its selective removal of bovine hemoglobin".nanotechnology 22.6(2011).