Polar-copolymerized approach based on horizontal polymerization on silica surface for preparation of polar-modified stationary phases

	Polar-copolymerized approach based on horizontal polymerization on silica surface for preparation of polar-modified stationary phases
	Guo, Zhimou 1; Wang, Chaoran 1; Liang, Tu 2; Liang, Xinmiao 1,2
刊名	journal of chromatography a
	2010-07-02
卷号	1217 期号:27 页码:4555-4560
关键词	Reversed-phase liquid chromatography Polar-modified stationary phases Polar-copolymerized Horizontal polymerization
英文摘要	a new approach for preparation of polar-modified reversed-phase liquid chromatography stationary phases was developed by using horizontal polymerization technique on silica surface, which was defined as "polar-copolymerized" approach. based on this new approach, a representative polar-copolymerized stationary phase composed of mixed n-octadecyl and chloropropyl (c18-c3c1) was synthesized. the resulting stationary phase named c18hce was characterized with elemental analysis and solid phase (13)c and (29)si nmr, which proved the chemistry of polar-copolymerized stationary phases. chromatographic evaluation and application of the c18hce were also investigated. the results of preliminary chromatographic evaluation demonstrated that the c18hce stationary phase exhibited 100% aqueous mobile phase compatibility, low silanol activity. in addition, the application results demonstrated that the c18hce had superior separation performance in alkaloids separation at acidic conditions compared to some commercial stationary phases. (c) 2010 elsevier b.v. all rights reserved.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	performance liquid-chromatography ; mixed trifunctional silanes ; embedded urea groups ; w. t. wang ; hplc ; retention ; alkyl ; stability ; alkaloids ; column
收录类别	SCI
语种	英语
WOS记录号	WOS:000279138600007
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/141682]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
推荐引用方式 GB/T 7714	Guo, Zhimou,Wang, Chaoran,Liang, Tu,et al. Polar-copolymerized approach based on horizontal polymerization on silica surface for preparation of polar-modified stationary phases[J]. journal of chromatography a,2010,1217(27):4555-4560.
APA	Guo, Zhimou,Wang, Chaoran,Liang, Tu,&Liang, Xinmiao.(2010).Polar-copolymerized approach based on horizontal polymerization on silica surface for preparation of polar-modified stationary phases.journal of chromatography a,1217(27),4555-4560.
MLA	Guo, Zhimou,et al."Polar-copolymerized approach based on horizontal polymerization on silica surface for preparation of polar-modified stationary phases".journal of chromatography a 1217.27(2010):4555-4560.