(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers

	(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers
	Deng, Qi-Liang ; Lun, Zhi-Hong ; Gao, Ru-Yu ; Zhang, Li-Hua ; Zhang, Wei-Bing ; Zhang, Yu-Kui
刊名	electrophoresis
	2006-11-01
卷号	27 期号:21 页码:4351-4358
关键词	capillary electrochromatography chiral recognition ibuprofen molecularly imprinted polymer
英文摘要	in this report, a novel preparation method of molecularly imprinted polymers (mips) for cec was developed. molecularly imprinted monolithic columns for (s)-ibuprofen were prepared and evaluated, in which charged entities responsible for establishing eof have been derived from gamma-methacryloxypropyltrimethoxysilane (gamma-maps), which was hydrolyzed following copolymerization with 4-vinylpyridine (4-vpy) and ethylene glycol dimethacrylate (edma). the eof and molecular recognition of the stationary phase were investigated in aqueous and nonaqueous media, respectively. the experimental results indicated that the material showed a reasonably stable eof and the prepared separation materials were capable of separating racemic ibuprofen, a task that could not be accomplished by mips prepared in parallel, using methacrylic acid (maa) as a functional monomer. the efficiency at ph 3.2 for the first-eluted enantiomer and the last-eluted enantiomer (the imprinted analyte) were 128 700 and 2100 plates/m, respectively.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	molecularly imprinted polymers ; selective stationary phases ; capillary electrochromatography ; liquid-chromatography ; electrophoresis ; recognition ; coatings
收录类别	SCI
语种	英语
WOS记录号	WOS:000242222500027
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/140130]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Nankai Univ, State Key Lab Element Organ Chem, Inst Element Organ Chem, Tianjin 300071, Peoples R China 2.Tianjin Univ Sci & Technol, Coll Sci, Tianjin, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China
推荐引用方式 GB/T 7714	Deng, Qi-Liang,Lun, Zhi-Hong,Gao, Ru-Yu,et al. (S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers[J]. electrophoresis,2006,27(21):4351-4358.
APA	Deng, Qi-Liang,Lun, Zhi-Hong,Gao, Ru-Yu,Zhang, Li-Hua,Zhang, Wei-Bing,&Zhang, Yu-Kui.(2006).(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers.electrophoresis,27(21),4351-4358.
MLA	Deng, Qi-Liang,et al."(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers".electrophoresis 27.21(2006):4351-4358.