Identification and analysis of retrogenes in the East Asian nematode Caenorhabditis sp 5 genome

CORC > 水生生物研究所 > 中科院水生所知识产出（2009年前） > 水生生物多样性与资源保护研究中心 > 期刊论文

	Identification and analysis of retrogenes in the East Asian nematode Caenorhabditis sp 5 genome
	Zhou, Kun 1; Zou, Ming 2; Duan, Mingyue 1; He, Shunping 3; Wang, Guoxiu 1
刊名	GENOME
	2015-07-01
卷号	58 期号:7 页码:349-355
关键词	Caenorhabditis sp 5 retrogenes chimeric genes genome
ISSN号	0831-2796
英文摘要	Retroposition, a molecular mechanism generating new genes, helps the formation of retrogenes and new functions, contributing to the evolution of genomes. The completed genome sequence of Caenorhabditis sp. 5 presents an excellent opportunity to identify retrogenes within C. sp. 5. We identified a total of 43 retrogenes and their corresponding chimeric genes. Among these, 29 were found to be intact retrogenes and 14 to be retropseudogenes. Unexpectedly, a high number of retrogenes appear to be functional and possibly involved in catalysis. Also, the proportion of the retrogenes forming chimeric structure is the highest among Caenorhabditis nematodes. In addition, the Ks distribution shows that C. sp. 5 has more retrogenes with high Ks, which may explain the high functionality of them among Caenorhabditis species. Our study will be helpful in the understanding of the functional and evolutionary impact of retroposition on C. sp. 5 genome.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biotechnology & Applied Microbiology ; Genetics & Heredity
研究领域[WOS]	Biotechnology & Applied Microbiology ; Genetics & Heredity
关键词[WOS]	PROCESSED PSEUDOGENES ; EVOLUTION ; DROSOPHILA ; GENES ; ORIGIN ; DIVERSITY ; YOUNG ; RETROPOSITION ; GENERATION ; BLAST
收录类别	SCI
语种	英语
WOS记录号	WOS:000361526800002
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/27211]
专题	水生生物研究所_水生生物多样性与资源保护研究中心_期刊论文
作者单位	1.Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China 2.Huazhong Agr Univ, Wuhan 430070, Peoples R China 3.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Kun,Zou, Ming,Duan, Mingyue,et al. Identification and analysis of retrogenes in the East Asian nematode Caenorhabditis sp 5 genome[J]. GENOME,2015,58(7):349-355.
APA	Zhou, Kun,Zou, Ming,Duan, Mingyue,He, Shunping,&Wang, Guoxiu.(2015).Identification and analysis of retrogenes in the East Asian nematode Caenorhabditis sp 5 genome.GENOME,58(7),349-355.
MLA	Zhou, Kun,et al."Identification and analysis of retrogenes in the East Asian nematode Caenorhabditis sp 5 genome".GENOME 58.7(2015):349-355.