Application of capillary electrophoresis in clinical chemistry: the clinical value of urinary modified nucleosides

	Application of capillary electrophoresis in clinical chemistry: the clinical value of urinary modified nucleosides
	Liebich, HM ; Lehmann, R ; Xu, G ; Wahl, HG ; Haring, HU
刊名	journal of chromatography b
	2000-08-04
卷号	745 期号:1 页码:189-196
关键词	nucleosides
英文摘要	urinary modified nucleosides were determined by capillary electrophoresis using a 300 mm sds-25 mm sodium tetraborate-50 mm sodium dihydrogenphosphate buffer. the nucleosides were extracted from urine by phenylboronate affinity gel chromatography. in cancer patients the levels of the modified nucleosides are generally elevated. by an artificial neural network method breast cancer patients were differentiated from normal individuals, which indicates that the modified nucleosides could be of clinical value as tumor markers. (c) 2000 elsevier science b.v. all rights reserved.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	performance liquid-chromatography ; transfer-rna modification ; serum pseudouridine ; degradation rates ; turnover ; marker ; ribonucleoside ; separation ; diagnosis ; cancer
收录类别	ISTP ; SCI
语种	英语
WOS记录号	WOS:000088810600015
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/138694]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Univ Tubingen, Med Klin, Abt 4, D-72076 Tubingen, Germany 2.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Peoples R China
推荐引用方式 GB/T 7714	Liebich, HM,Lehmann, R,Xu, G,et al. Application of capillary electrophoresis in clinical chemistry: the clinical value of urinary modified nucleosides[J]. journal of chromatography b,2000,745(1):189-196.
APA	Liebich, HM,Lehmann, R,Xu, G,Wahl, HG,&Haring, HU.(2000).Application of capillary electrophoresis in clinical chemistry: the clinical value of urinary modified nucleosides.journal of chromatography b,745(1),189-196.
MLA	Liebich, HM,et al."Application of capillary electrophoresis in clinical chemistry: the clinical value of urinary modified nucleosides".journal of chromatography b 745.1(2000):189-196.