Factors affecting membrane fouling in filtration of Saccharomyces cerevisiae in an internal ceramic filter bioreactor

	Factors affecting membrane fouling in filtration of Saccharomyces cerevisiae in an internal ceramic filter bioreactor
	Zhang, W ; Park, BG ; Chang, YK ; Chang, HN ; Yu, XJ ; Yuan, Q
刊名	bioprocess engineering
	1998-04-01
卷号	18 期号:4 页码:317-322
英文摘要	filtration of ethanol fermentation medium and broth by using symmetric and asymmetric ceramic membranes has been studied in an internal filter bioreactor. factors studied included membrane structure and pore size, medium sterilization, and concentrations of glucose, yeast extract in the medium, yeast cell and protein in broth. the aim was to determine the main factors responsible for the decline in filtration performance during ethanol fermentation by saccharomyces cerevisiae. flux index (fi) of a new concept has been developed to evaluate the degree of flux decline during the membrane fouling process. fi was defined as the ratio of the membrane flux at certain filtration time (t = t) to the initial(t = -0) flux of pure water, not the initial (t = +0) flux of the test fluid. flux with sterilized medium was approximately two-fold higher than that with unsterilized medium although the reason could not be explained clearly. glucose, interaction between glucose and yeast extract, yeast cells, and proteins in fermentation broth were found to play an important part in membrane fouling. fi of the symmetric membrane decreased to a less extent than that of the asymmetric membrane with increasing glucose concentration. but, the result with various yeast cell concentrations turned out to be contrary. fouling was more serious for asymmetric membrane during the filtration of fermentation supernatant. this was thought to be due to different fouling mechanisms for the two types of membrane.
WOS标题词	science & technology ; life sciences & biomedicine ; technology
类目[WOS]	biotechnology & applied microbiology ; engineering, chemical
研究领域[WOS]	biotechnology & applied microbiology ; engineering
关键词[WOS]	cell retention culture ; microfiltration ; fermentation ; separation ; reactor
收录类别	SCI
语种	英语
WOS记录号	WOS:000073534000013
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/138175]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Korea Adv Inst Sci & Technol, Dept Chem Engn, Taejon 305701, South Korea 2.Korea Adv Inst Sci & Technol, Bioproc Engn Res Ctr, Taejon 305701, South Korea 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dept Biochem Engn, Dalian 116012, Peoples R China
推荐引用方式 GB/T 7714	Zhang, W,Park, BG,Chang, YK,et al. Factors affecting membrane fouling in filtration of Saccharomyces cerevisiae in an internal ceramic filter bioreactor[J]. bioprocess engineering,1998,18(4):317-322.
APA	Zhang, W,Park, BG,Chang, YK,Chang, HN,Yu, XJ,&Yuan, Q.(1998).Factors affecting membrane fouling in filtration of Saccharomyces cerevisiae in an internal ceramic filter bioreactor.bioprocess engineering,18(4),317-322.
MLA	Zhang, W,et al."Factors affecting membrane fouling in filtration of Saccharomyces cerevisiae in an internal ceramic filter bioreactor".bioprocess engineering 18.4(1998):317-322.