Biomimetic glycopolymers tethered gold nanoparticles: Preparation, self-assembly and lectin recognition properties

	Biomimetic glycopolymers tethered gold nanoparticles: Preparation, self-assembly and lectin recognition properties
	Pei, Danfeng 1; Li, Yanchun 2; Huang, Qingrong 3; Ren, Qu 4; Li, Fan 1; Shi, Tongfei 1
刊名	COLLOIDS AND SURFACES B-BIOINTERFACES
	2015-02-01
卷号	126 页码:367-373
关键词	Glycopolymer Degradable Gold nanoparticle Self-assembly Lectin recognition
英文摘要	Biomimetic glycopolymers poly(gluconamidoethylmethacrylate)-b-poly(epsilon-caprolactone)-b-poly (gluconamidoethylmethacrylate) with degradable disulfide groups in the backbone (PGAMA-PCL-SS-PCL-PGAMA) were synthesized by the combination of ring opening polymerization (ROP) and atom transfer radical polymerization (ATRP). The internal disulfide bonds were cleaved by reduction with DL-dithiothreitol to yield the corresponding thiol terminated glycopolymers. The thiol terminated glycopolymers were effectively anchored on the surface of gold nanoparticles to prepare the biomimetic glycopolymers modified gold nanoparticles (Gly@Au NPs). Moreover, the properties of the Gly@Au NPs in aqueous solution were investigated. Transmission electron microscopy (TEM) analysis revealed that the self-assembly morphology of the Gly@Au NPs can be fine-tuned, from irregular clusters to spherical aggregates, by changing the weight fraction of the hydrophobic PCL block. Furthermore, the Gly@Au NPs had specific recognition with Concanavalin A (Con A). (C) 2014 Elsevier B.V. All rights reserved.
收录类别	SCI
语种	英语
公开日期	2015-11-02
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/28266]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Jilin Univ, Hosp 1, Dept Pediat Resp Med, Changchun 130021, Jilin Province, Peoples R China 3.Rutgers State Univ, Cook Coll, Dept Food Sci, New Brunswick, NJ 08901 USA 4.Air Force Gen Hosp, Clin Lab Ctr, Beijing 100142, Peoples R China
推荐引用方式 GB/T 7714	Pei, Danfeng,Li, Yanchun,Huang, Qingrong,et al. Biomimetic glycopolymers tethered gold nanoparticles: Preparation, self-assembly and lectin recognition properties[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2015,126:367-373.
APA	Pei, Danfeng,Li, Yanchun,Huang, Qingrong,Ren, Qu,Li, Fan,&Shi, Tongfei.(2015).Biomimetic glycopolymers tethered gold nanoparticles: Preparation, self-assembly and lectin recognition properties.COLLOIDS AND SURFACES B-BIOINTERFACES,126,367-373.
MLA	Pei, Danfeng,et al."Biomimetic glycopolymers tethered gold nanoparticles: Preparation, self-assembly and lectin recognition properties".COLLOIDS AND SURFACES B-BIOINTERFACES 126(2015):367-373.