Supramolecular helical nanofibers assembled from a pyridinium-functionalized methyl glycyrrhetate amphiphile

	Supramolecular helical nanofibers assembled from a pyridinium-functionalized methyl glycyrrhetate amphiphile
	Gao, Yuxia 1; Hao, Jie 1; Wu, Jindan 1; Zhang, Xun 1; Hu, Jun 2; Ju, Yong 1
刊名	NANOSCALE
	2015
卷号	7 期号:32 页码:13568-13575
英文摘要	A glycyrrhetate-containing amphiphile, MGP (1-[2-(methyl glycyrrhetate)-2-oxoethyl] pyridinium bromide), has been synthesized, and found to assemble into supramolecular helical nanofibers in chloroform/aromatic solvents, which are primarily driven by pi-pi stacking, van der Waals forces, and hydrophobic interactions. During the assembly process, MGP stacked into J-aggregates resulting in the sequestration of the hydrophilic pyridinium cation within the interior with the concomitant projection of its hydrophobic skeleton on the outside surface. Ultimately, this protrusion generated a staggered angle due to the steric hindrance between stacked molecules. This staggered angle further led to molecular misalignments and the formation of helical fibrils, which could twist with each other to fabricate larger helical fibers. Consequently, a gel was formed by intertwining these nanofibers into three-dimensional networks. Using this strategy, we found that other triterpenoid-tailored pyridinium amphiphiles are also potential scaffolds for supramolecular helical structures. This work provides a facile approach for the fabrication of supramolecular macroscopic chiral nanostructures that originate from natural products.
收录类别	SCI
语种	英语
公开日期	2015-10-27
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/27735]
专题	化学研究所_高分子物理与化学实验室
作者单位	1.Tsinghua Univ, Dept Chem, Minist Educ, Key Lab Bioorgan Phosphorus Chem & Chem Biol, Beijing 100084, Peoples R China 2.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China
推荐引用方式 GB/T 7714	Gao, Yuxia,Hao, Jie,Wu, Jindan,et al. Supramolecular helical nanofibers assembled from a pyridinium-functionalized methyl glycyrrhetate amphiphile[J]. NANOSCALE,2015,7(32):13568-13575.
APA	Gao, Yuxia,Hao, Jie,Wu, Jindan,Zhang, Xun,Hu, Jun,&Ju, Yong.(2015).Supramolecular helical nanofibers assembled from a pyridinium-functionalized methyl glycyrrhetate amphiphile.NANOSCALE,7(32),13568-13575.
MLA	Gao, Yuxia,et al."Supramolecular helical nanofibers assembled from a pyridinium-functionalized methyl glycyrrhetate amphiphile".NANOSCALE 7.32(2015):13568-13575.