Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures
Du, Pengcheng1,2; Wang TM(王廷梅)3; Liu P(刘鹏)1,2
刊名Colloids and Surfaces B: Biointerfaces
2013
卷号102页码:1-8
ISSN号0927-7765
通讯作者刘鹏
英文摘要The magnetic-targeting stimuli-responsive hollow polymeric microspheres show unique performance as the intelligent carriers for the site specific controlled delivery of drugs or genes. In the work, the well-defied dual-responsive double-walled hollow microspheres with movable magnetic cores were prepared from the penta-layer onion-shaped core-shell microspheres. Their double-walled shells were independent, with the pH-responsive crosslinked poly(methacrylic acid) (PMAA) layer as the inner shell and the temperature responsive crosslinked poly(N-isopropylacrylamide) (PNIPAM) layer as the outer shell. The combination of the pH and temperature dual-responsive and the magnetic-targeting function make the hollow microspheres to be the most promising intelligent carriers in the biomedical fields.
学科主题材料科学与物理化学
收录类别SCI
资助信息the National Natural Science Foundation of China (Grant No. 20904017);the Program for New Century Excellent Talents in University (Grant No. NCET-09-0441);the Fundamental Research Funds for the Central Universities (Grant No. lzujbky-2012-k12)
语种英语
WOS记录号WOS:000313301200001
内容类型期刊论文
源URL[http://210.77.64.217/handle/362003/13225]  
专题兰州化学物理研究所_先进润滑与防护材料研究发展中心
兰州化学物理研究所_固体润滑国家重点实验室
作者单位1.Lanzhou Univ, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China
2.Lanzhou Univ, Inst Polymer Sci & Engn, Coll Chem & Chem Engn, Lanzhou 730000, Peoples R China
3.Chinese Acad Sci, State Key Lab Solid Lubricat, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China
推荐引用方式
GB/T 7714
Du, Pengcheng,Wang TM,Liu P. Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures[J]. Colloids and Surfaces B: Biointerfaces,2013,102:1-8.
APA Du, Pengcheng,Wang TM,&Liu P.(2013).Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures.Colloids and Surfaces B: Biointerfaces,102,1-8.
MLA Du, Pengcheng,et al."Double-walled hollow polymeric microspheres with independent pH and temperature dual-responsive and magnetic-targeting function from onion-shaped core-shell structures".Colloids and Surfaces B: Biointerfaces 102(2013):1-8.
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