Novel registration for microcomputed tomography and bioluminescence imaging based on iterated optimal projection

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Novel registration for microcomputed tomography and bioluminescence imaging based on iterated optimal projection
	Ma, Xibo1 ; Deng, Kexin 2; Xue, Zhenwen 1; Liu, Xueyan 3; Zhu, Shouping 2; Qin, Chenghu 1; Yang, Xin 1; Tian, Jie1
刊名	JOURNAL OF BIOMEDICAL OPTICS
	2013-02-01
卷号	18 期号:2 页码:-
关键词	bioluminescence tomography universal registration method iterated optimal projection three-dimensional reconstruction based on registration impact on the reconstruction of registration
英文摘要	As a high-sensitivity imaging modality, bioluminescence tomography can reconstruct the three-dimensional (3-D) location of an internal luminescent source based on the 3-D surface light distribution. However, we can only get the multi-orientation two-dimensional (2-D) bioluminescence distribution in the experiments. Therefore, developing an accurate universal registration method is essential for following bioluminescent source reconstruction. We can then map the multi-orientation 2-D bioluminescence distribution to the 3-D surface derived from anatomical information with it. We propose a 2-D -to-3-D registration method based on iterated optimal projection and applied it in a registration and reconstruction study of three transgenic mice. Compared with traditional registration methods based on the fixed points, our method was independent of the markers and the registration accuracy of the three experiments was improved by 0.3, 0.5, and 0.4 pixels, respectively. In addition, based on the above two registration results using the two registration methods, we reconstructed the 3-D location of the inner bioluminescent source in the three transgenic mice. The reconstruction results showed that the average error distance between the center of the reconstructed element and the center of the real element were reduced by 0.32, 0.48, and 0.39 mm, respectively. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. [DOI: 10.1117/1.JBO.18.2.026013]
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]	Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]	Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]	AFFINE REGISTRATION ; EDGE-DETECTION ; RECONSTRUCTION ; FRAMEWORK ; PLATFORM ; IMAGES ; MEDIA ; LIGHT
收录类别	SCI
语种	英语
WOS记录号	WOS:000315159900027
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/4074]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Chinese Acad Sci, Intelligent Med Res Ctr, Inst Automat, Beijing 100190, Peoples R China 2.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 3.Northeastern Univ, Sinodutch Biomed & Informat Engn Sch, Shenyang 110819, Peoples R China
推荐引用方式 GB/T 7714	Ma, Xibo,Deng, Kexin,Xue, Zhenwen,et al. Novel registration for microcomputed tomography and bioluminescence imaging based on iterated optimal projection[J]. JOURNAL OF BIOMEDICAL OPTICS,2013,18(2):-.
APA	Ma, Xibo.,Deng, Kexin.,Xue, Zhenwen.,Liu, Xueyan.,Zhu, Shouping.,...&Tian, Jie.(2013).Novel registration for microcomputed tomography and bioluminescence imaging based on iterated optimal projection.JOURNAL OF BIOMEDICAL OPTICS,18(2),-.
MLA	Ma, Xibo,et al."Novel registration for microcomputed tomography and bioluminescence imaging based on iterated optimal projection".JOURNAL OF BIOMEDICAL OPTICS 18.2(2013):-.